Acute interstitial nephritis, a rare complication of Giardiasis
Acute interstitial nephritis is a relevant cause of acute renal failure. Drugs are the predominant cause, followed by infections and idiopathic lesions. Acute interstitial nephritis as a form of hypersensitivity reaction is an uncommon manifestation in the setting of human parasitic infections. We p...
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MDPI AG
2011-12-01
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Online Access: | https://www.clinicsandpractice.org/index.php/cp/article/view/344 |
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doaj-af64404684084e2db8a9e06393542ef22021-04-02T17:40:04ZengMDPI AGClinics and Practice2039-72752039-72832011-12-012110.4081/cp.2012.e6143Acute interstitial nephritis, a rare complication of GiardiasisAntonio De Pascalis0Erasmo Buongiorno1Nephrology, Dialysis and Renal Transplantation Unit, V. Fazzi Hospital, LecceNephrology, Dialysis and Renal Transplantation Unit, V. Fazzi Hospital, LecceAcute interstitial nephritis is a relevant cause of acute renal failure. Drugs are the predominant cause, followed by infections and idiopathic lesions. Acute interstitial nephritis as a form of hypersensitivity reaction is an uncommon manifestation in the setting of human parasitic infections. We present a case of acute interstitial nephritis in association with Giardia infection in a 54-year-old woman who developed an impairment of renal function after a prolonged period of slight fever and diarrhea. After an attempt to recover renal impairment by vigorous rehydratation, because of the unclear origin of the persisting renal failure, a percutaneous renal biopsy was performed and a diagnosis of severe acute interstitial nephritis was made. Steroid therapy was started and after six weeks, renal function had completely recovered. In cases of unexplained renal failure in patients affected by parasitic infections, interstitial nephritis should be considered and it is our opinion that a renal biopsy should be always performed.https://www.clinicsandpractice.org/index.php/cp/article/view/344acute renal failureacute interstitial nephritisinfections. |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Antonio De Pascalis Erasmo Buongiorno |
spellingShingle |
Antonio De Pascalis Erasmo Buongiorno Acute interstitial nephritis, a rare complication of Giardiasis Clinics and Practice acute renal failure acute interstitial nephritis infections. |
author_facet |
Antonio De Pascalis Erasmo Buongiorno |
author_sort |
Antonio De Pascalis |
title |
Acute interstitial nephritis, a rare complication of Giardiasis |
title_short |
Acute interstitial nephritis, a rare complication of Giardiasis |
title_full |
Acute interstitial nephritis, a rare complication of Giardiasis |
title_fullStr |
Acute interstitial nephritis, a rare complication of Giardiasis |
title_full_unstemmed |
Acute interstitial nephritis, a rare complication of Giardiasis |
title_sort |
acute interstitial nephritis, a rare complication of giardiasis |
publisher |
MDPI AG |
series |
Clinics and Practice |
issn |
2039-7275 2039-7283 |
publishDate |
2011-12-01 |
description |
Acute interstitial nephritis is a relevant cause of acute renal failure. Drugs are the predominant cause, followed by infections and idiopathic lesions. Acute interstitial nephritis as a form of hypersensitivity reaction is an uncommon manifestation in the setting of human parasitic infections. We present a case of acute interstitial nephritis in association with Giardia infection in a 54-year-old woman who developed an impairment of renal function after a prolonged period of slight fever and diarrhea. After an attempt to recover renal impairment by vigorous rehydratation, because of the unclear origin of the persisting renal failure, a percutaneous renal biopsy was performed and a diagnosis of severe acute interstitial nephritis was made. Steroid therapy was started and after six weeks, renal function had completely recovered. In cases of unexplained renal failure in patients affected by parasitic infections, interstitial nephritis should be considered and it is our opinion that a renal biopsy should be always performed. |
topic |
acute renal failure acute interstitial nephritis infections. |
url |
https://www.clinicsandpractice.org/index.php/cp/article/view/344 |
work_keys_str_mv |
AT antoniodepascalis acuteinterstitialnephritisararecomplicationofgiardiasis AT erasmobuongiorno acuteinterstitialnephritisararecomplicationofgiardiasis |
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1721553620967620608 |