The GLP-1 Receptor Agonist Exenatide Ameliorates Bone Composition and Tissue Material Properties in High Fat Fed Diabetic Mice
Type 2 diabetes mellitus (T2DM) has recently been recognized as a significant risk factor for bone fragility. Careful investigations of bone mechanical properties in human studies suggested possible alterations of bone composition, although this axis has poorly been investigated. The main aim of thi...
Main Authors: | Sity Aishah Mansur, Aleksandra Mieczkowska, Peter R. Flatt, Daniel Chappard, Nigel Irwin, Guillaume Mabilleau |
---|---|
Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2019-02-01
|
Series: | Frontiers in Endocrinology |
Subjects: | |
Online Access: | https://www.frontiersin.org/article/10.3389/fendo.2019.00051/full |
Similar Items
-
GLP-2 administration in ovariectomized mice enhances collagen maturity but did not improve bone strength
by: B. Gobron, et al.
Published: (2020-06-01) -
Exenatide Improves Bone Quality in a Murine Model of Genetically Inherited Type 2 Diabetes Mellitus
by: Marie Pereira, et al.
Published: (2017-11-01) -
[Gly²]-GLP-2, But Not Glucagon or [D-Ala²]-GLP-1, Controls Collagen Crosslinking in Murine Osteoblast Cultures
by: Aleksandra Mieczkowska, et al.
Published: (2021-08-01) -
A Pilot Study Showing Acute Inhibitory Effect of GLP‐1 on the Bone Resorption Marker CTX in Humans
by: Anne Nissen, et al.
Published: (2019-10-01) -
Abrasion of 6 dentifrices measured by vertical scanning interference microscopy
by: Florence Pascaretti-Grizon, et al.
Published: (2013-09-01)