Unusual, stable replicating viruses generated from mumps virus cDNA clones.
In reverse genetic experiments we have isolated recombinant mumps viruses (rMuV) that carry large numbers of mutations clustered in small parts of their genome, which are not caused by biased hyper-mutation. In two separate experiments we obtained such recombinant viruses: one virus had 11 mutations...
Main Authors: | Connor Bamford, Elizabeth Wignall-Fleming, Vattipally B Sreenu, Richard Randall, Paul Duprex, Bertus Rima |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2019-01-01
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Series: | PLoS ONE |
Online Access: | https://doi.org/10.1371/journal.pone.0219168 |
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