Pre-plaque conformational changes in Alzheimer’s disease-linked Aβ and APP

Studying the physiological confirmation of amyloid β (Aβ) and amyloid precursor protein (APP) often uses techniques that could disrupt their conformation. Here, the authors use non-destructive microscopy approaches to study the confirmation of Aβ and APP in mouse models of Alzheimer’s disease.

Bibliographic Details
Main Authors: O. Klementieva, K. Willén, I. Martinsson, B. Israelsson, A. Engdahl, J. Cladera, P. Uvdal, G. K. Gouras
Format: Article
Language:English
Published: Nature Publishing Group 2017-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms14726