Genome-wide associations between genetic and epigenetic variation influence mRNA expression and insulin secretion in human pancreatic islets.

Genetic and epigenetic mechanisms may interact and together affect biological processes and disease development. However, most previous studies have investigated genetic and epigenetic mechanisms independently, and studies examining their interactions throughout the human genome are lacking. To iden...

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Bibliographic Details
Main Authors: Anders H Olsson, Petr Volkov, Karl Bacos, Tasnim Dayeh, Elin Hall, Emma A Nilsson, Claes Ladenvall, Tina Rönn, Charlotte Ling
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-11-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC4222689?pdf=render