Disseminated intravascular coagulation in perinatal medicine
Introduction. Disseminated intravascular coagulation (DIC) is an acquired syndrome characterized by intravascular activation of blood clotting without specific localization and arising from various causes. DIC is the most complex and high-priority problem in contemporary clinical medicine including...
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doaj-af78f7e164c8497b9bf7b3217931174d2021-07-28T13:44:41ZrusIRBIS LLCАкушерство, гинекология и репродукция2313-73472500-31942020-04-01141566810.17749/2313-7347.2020.14.1.56-68537Disseminated intravascular coagulation in perinatal medicineM. A. Mingalimov0K. N. Grigorieva1M. V. Tretyakova2I. Elalamy3Kh. G. Sultangadzhieva4V. O. Bitsadze5J. Kh. Khizroeva6A. D. Makatsariya7Sechenov UniversitySechenov UniversityMedical Center, LLCSechenov University; Medicine Sorbonne University; HospitaI TenonSechenov UniversitySechenov UniversitySechenov UniversitySechenov UniversityIntroduction. Disseminated intravascular coagulation (DIC) is an acquired syndrome characterized by intravascular activation of blood clotting without specific localization and arising from various causes. DIC is the most complex and high-priority problem in contemporary clinical medicine including obstetrics and perinatology. DIC significance is related to its peak perinatal mortality, as well as a large rate of complications during childbirth and postpartum period.Aim: to conduct comprehensive data assessment related to DIC pathogenesis and management in pregnant women and newborns.Materials and methods. A search for DIC-related publications within the past 10 years was conducted in international research databases: Scientific Electronic Library Online eLibrary, Google Scholar, ScienceDirect, Cochrane Library, PubMed/Medline. The data regarding DIC diagnostic criteria and markers, as well as current approach to its treatment are presented.Results. DIC may be considered as one of the causes resulting in massive obstetric bleeding. The majority of pregnancy-related complications is manifested as preeclampsia, premature detachment of normally situated placenta and anaphylactoid syndrome of pregnancy. Any massive bleeding should be perceived as hemorrhage resulting from the DIC progression.Conclusion. Knowledge of the DIC pathogenetic mechanisms is necessary for conducting a differential diagnosis and applying timely treatment.https://www.gynecology.su/jour/article/view/625disseminated intravascular coagulationdicperinatal medicinethromboseshemostatic disordersanticoagulant therapygestationneonatal thromboses |
collection |
DOAJ |
language |
Russian |
format |
Article |
sources |
DOAJ |
author |
M. A. Mingalimov K. N. Grigorieva M. V. Tretyakova I. Elalamy Kh. G. Sultangadzhieva V. O. Bitsadze J. Kh. Khizroeva A. D. Makatsariya |
spellingShingle |
M. A. Mingalimov K. N. Grigorieva M. V. Tretyakova I. Elalamy Kh. G. Sultangadzhieva V. O. Bitsadze J. Kh. Khizroeva A. D. Makatsariya Disseminated intravascular coagulation in perinatal medicine Акушерство, гинекология и репродукция disseminated intravascular coagulation dic perinatal medicine thromboses hemostatic disorders anticoagulant therapy gestation neonatal thromboses |
author_facet |
M. A. Mingalimov K. N. Grigorieva M. V. Tretyakova I. Elalamy Kh. G. Sultangadzhieva V. O. Bitsadze J. Kh. Khizroeva A. D. Makatsariya |
author_sort |
M. A. Mingalimov |
title |
Disseminated intravascular coagulation in perinatal medicine |
title_short |
Disseminated intravascular coagulation in perinatal medicine |
title_full |
Disseminated intravascular coagulation in perinatal medicine |
title_fullStr |
Disseminated intravascular coagulation in perinatal medicine |
title_full_unstemmed |
Disseminated intravascular coagulation in perinatal medicine |
title_sort |
disseminated intravascular coagulation in perinatal medicine |
publisher |
IRBIS LLC |
series |
Акушерство, гинекология и репродукция |
issn |
2313-7347 2500-3194 |
publishDate |
2020-04-01 |
description |
Introduction. Disseminated intravascular coagulation (DIC) is an acquired syndrome characterized by intravascular activation of blood clotting without specific localization and arising from various causes. DIC is the most complex and high-priority problem in contemporary clinical medicine including obstetrics and perinatology. DIC significance is related to its peak perinatal mortality, as well as a large rate of complications during childbirth and postpartum period.Aim: to conduct comprehensive data assessment related to DIC pathogenesis and management in pregnant women and newborns.Materials and methods. A search for DIC-related publications within the past 10 years was conducted in international research databases: Scientific Electronic Library Online eLibrary, Google Scholar, ScienceDirect, Cochrane Library, PubMed/Medline. The data regarding DIC diagnostic criteria and markers, as well as current approach to its treatment are presented.Results. DIC may be considered as one of the causes resulting in massive obstetric bleeding. The majority of pregnancy-related complications is manifested as preeclampsia, premature detachment of normally situated placenta and anaphylactoid syndrome of pregnancy. Any massive bleeding should be perceived as hemorrhage resulting from the DIC progression.Conclusion. Knowledge of the DIC pathogenetic mechanisms is necessary for conducting a differential diagnosis and applying timely treatment. |
topic |
disseminated intravascular coagulation dic perinatal medicine thromboses hemostatic disorders anticoagulant therapy gestation neonatal thromboses |
url |
https://www.gynecology.su/jour/article/view/625 |
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