HIV-1 Tat protein induces DNA damage in human peripheral blood B-lymphocytes via mitochondrial ROS production
Human immunodeficiency virus (HIV) infection is associated with B-cell malignancies in patients though HIV-1 is not able to infect B-cells. The rate of B-cell lymphomas in HIV-infected individuals remains high even under the combined antiretroviral therapy (cART) that reconstitutes the immune functi...
Main Authors: | Rawan El-Amine, Diego Germini, Vlada V. Zakharova, Tatyana Tsfasman, Eugene V. Sheval, Ruy A.N. Louzada, Corinne Dupuy, Chrystèle Bilhou-Nabera, Aline Hamade, Fadia Najjar, Eric Oksenhendler, Marс Lipinski, Boris V. Chernyak, Yegor S. Vassetzky |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2018-05-01
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Series: | Redox Biology |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2213231717306055 |
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