Collaborative study of thresholds for mutagens: proposal of a typical protocol for detection of hormetic responses in cytotoxicity tests

Collaborative study of thresholds for mutagens: proposal of a typical protocol for detection of hormetic responses in cytotoxicity tests

Abstract Background According to the linear no-threshold model (LNT), even the smallest amount of radiation is hazardous. Although the LNT is not based on solid data, this hypothesis has been applied to mutagens and carcinogens. As a result, it has been postulated that there are no thresholds for th...

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Bibliographic Details
Main Authors: Shizuyo Sutou, Akiko Koeda, Kana Komatsu, Toshiyuki Shiragiku, Hiroshi Seki, Kohji Yamakage, Takeru Niitsuma, Toshiyuki Kudo, Akihiro Wakata, (The Mammalian Mutagenicity Study Group
Format: Article
Language:English
Published: BMC 2018-10-01
Series:Genes and Environment
Subjects:
Adaptive response
CHL/IU
Ethyl methanesulfonate
HeLa S3
Hormesis
Mitomycin C
Online Access:http://link.springer.com/article/10.1186/s41021-018-0108-1

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