Nervous System of Periplaneta americana Cockroach as a Model in Toxinological Studies: A Short Historical and Actual View

Nervous System of Periplaneta americana Cockroach as a Model in Toxinological Studies: A Short Historical and Actual View

Nervous system of Periplaneta americana cockroach is used in a wide range of pharmacological studies, including electrophysiological techniques. This paper presents its role as a preparation in the development of toxinological studies in the following electrophysiological methods: double-oil-gap tec...

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Main Authors: Maria Stankiewicz, Marcin Dąbrowski, Maria Elena de Lima
Format: Article
Language:English
Published: Hindawi Limited 2012-01-01
Series:Journal of Toxicology
Online Access:http://dx.doi.org/10.1155/2012/143740
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spelling doaj-aff724f7b9c74f869040e40c88550fd42020-11-24T22:22:40ZengHindawi LimitedJournal of Toxicology1687-81911687-82052012-01-01201210.1155/2012/143740143740Nervous System of Periplaneta americana Cockroach as a Model in Toxinological Studies: A Short Historical and Actual ViewMaria Stankiewicz0Marcin Dąbrowski1Maria Elena de Lima2Biophysics Laboratory, Institute of General and Molecular Biology, N. Copernicus University, 87-100 Torun, PolandBiophysics Laboratory, Institute of General and Molecular Biology, N. Copernicus University, 87-100 Torun, PolandDepartamento de Bioquímica e Imunologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, 31270-901 MG, BrazilNervous system of Periplaneta americana cockroach is used in a wide range of pharmacological studies, including electrophysiological techniques. This paper presents its role as a preparation in the development of toxinological studies in the following electrophysiological methods: double-oil-gap technique on isolated giant axon, patch-clamp on DUM (dorsal unpaired median) neurons, microelectrode technique in situ conditions on axon in connective and DUM neurons in ganglion, and single-fiber oil-gap technique on last abdominal ganglion synapse. At the end the application of cockroach synaptosomal preparation is mentioned.http://dx.doi.org/10.1155/2012/143740
collection DOAJ
language English
format Article
sources DOAJ
author Maria Stankiewicz
Marcin Dąbrowski
Maria Elena de Lima
spellingShingle Maria Stankiewicz
Marcin Dąbrowski
Maria Elena de Lima
Nervous System of Periplaneta americana Cockroach as a Model in Toxinological Studies: A Short Historical and Actual View
Journal of Toxicology
author_facet Maria Stankiewicz
Marcin Dąbrowski
Maria Elena de Lima
author_sort Maria Stankiewicz
title Nervous System of Periplaneta americana Cockroach as a Model in Toxinological Studies: A Short Historical and Actual View
title_short Nervous System of Periplaneta americana Cockroach as a Model in Toxinological Studies: A Short Historical and Actual View
title_full Nervous System of Periplaneta americana Cockroach as a Model in Toxinological Studies: A Short Historical and Actual View
title_fullStr Nervous System of Periplaneta americana Cockroach as a Model in Toxinological Studies: A Short Historical and Actual View
title_full_unstemmed Nervous System of Periplaneta americana Cockroach as a Model in Toxinological Studies: A Short Historical and Actual View
title_sort nervous system of periplaneta americana cockroach as a model in toxinological studies: a short historical and actual view
publisher Hindawi Limited
series Journal of Toxicology
issn 1687-8191
1687-8205
publishDate 2012-01-01
description Nervous system of Periplaneta americana cockroach is used in a wide range of pharmacological studies, including electrophysiological techniques. This paper presents its role as a preparation in the development of toxinological studies in the following electrophysiological methods: double-oil-gap technique on isolated giant axon, patch-clamp on DUM (dorsal unpaired median) neurons, microelectrode technique in situ conditions on axon in connective and DUM neurons in ganglion, and single-fiber oil-gap technique on last abdominal ganglion synapse. At the end the application of cockroach synaptosomal preparation is mentioned.
url http://dx.doi.org/10.1155/2012/143740
work_keys_str_mv AT mariastankiewicz nervoussystemofperiplanetaamericanacockroachasamodelintoxinologicalstudiesashorthistoricalandactualview
AT marcindabrowski nervoussystemofperiplanetaamericanacockroachasamodelintoxinologicalstudiesashorthistoricalandactualview
AT mariaelenadelima nervoussystemofperiplanetaamericanacockroachasamodelintoxinologicalstudiesashorthistoricalandactualview
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