DNA Methylation-Based Estimates of Circulating Leukocyte Composition for Predicting Colorectal Cancer Survival: A Prospective Cohort Study

DNA Methylation-Based Estimates of Circulating Leukocyte Composition for Predicting Colorectal Cancer Survival: A Prospective Cohort Study

Leukocytes are involved in the progression of colorectal cancer (CRC). The proportion of six major leukocyte subtypes can be estimated using epigenome-wide DNA methylation (DNAm) data from stored blood samples. Whether the composition of circulating leukocytes can be used as a prognostic factor is u...

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Bibliographic Details
Main Authors: Xīn Gào, Yan Zhang, Xiangwei Li, Lina Jansen, Elizabeth Alwers, Melanie Bewerunge-Hudler, Matthias Schick, Jenny Chang-Claude, Michael Hoffmeister, Hermann Brenner
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Cancers
Subjects:
DNA methylation
circulating leukocytes
colorectal cancer
prognosis
Online Access:https://www.mdpi.com/2072-6694/13/12/2948

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