Metastatic Basal Cell Carcinoma: A Rare Manifestation of a Common Disease

Introduction. Basal cell carcinoma (BCC) is considered the most common malignancy in Caucasians. It constituted about 80% of all nonmelanoma skin tumors and, despite its high prevalence, is an extremely rare occurrence of metastases, with incidence rates varying from 0.0028% to 0.55%. Case Report. A...

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Main Authors: Paola Piva de Freitas, César Galusni Senna, Mayara Tabai, Carlos Takahiro Chone, Albina Altemani
Format: Article
Language:English
Published: Hindawi Limited 2017-01-01
Series:Case Reports in Medicine
Online Access:http://dx.doi.org/10.1155/2017/8929745
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spelling doaj-b0146051c8d94eee92820f1e157fb7f72020-11-24T23:59:46ZengHindawi LimitedCase Reports in Medicine1687-96271687-96352017-01-01201710.1155/2017/89297458929745Metastatic Basal Cell Carcinoma: A Rare Manifestation of a Common DiseasePaola Piva de Freitas0César Galusni Senna1Mayara Tabai2Carlos Takahiro Chone3Albina Altemani4Department of Otolaryngology Head and Neck, Faculty of Medical Sciences, University of Campinas (UNICAMP), Campinas, SP, BrazilDepartment of Otolaryngology Head and Neck, Faculty of Medical Sciences, University of Campinas (UNICAMP), Campinas, SP, BrazilDepartment of Otolaryngology Head and Neck, Faculty of Medical Sciences, University of Campinas (UNICAMP), Campinas, SP, BrazilDepartment of Otolaryngology Head and Neck, Faculty of Medical Sciences, University of Campinas (UNICAMP), Campinas, SP, BrazilDepartment of Pathological Anatomy, Faculty of Medical Sciences, University of Campinas (UNICAMP), Campinas, SP, BrazilIntroduction. Basal cell carcinoma (BCC) is considered the most common malignancy in Caucasians. It constituted about 80% of all nonmelanoma skin tumors and, despite its high prevalence, is an extremely rare occurrence of metastases, with incidence rates varying from 0.0028% to 0.55%. Case Report. A 58-year-old male patient with BCC on the left nasolabial sulcus for 17 years, reporting 3 previous excisions, evolved with local recurrence. A new procedure was performed, and anatomopathological study confirmed sclerosing BCC. Seven months later, he presented with a mass in the left submandibular region. Combined positron-emission tomography and computed tomography (PET-CT) showed cervical hypercaptation in the left cervical level I and vertebral body of L5. Excision of the cervical lesion was performed with diagnosis of sclerosing BCC compromising the submandibular gland. Biopsy of the lumbar lesion was found to be compatible with bone metastasis. Conclusion. BCC represents a very common entity, and the presence of metastasis, although infrequent, must be proposed because of the greater morbidity and mortality of this complication. This case shows the importance of early diagnosis and intervention in BCC as a way to avoid unfavorable outcomes.http://dx.doi.org/10.1155/2017/8929745
collection DOAJ
language English
format Article
sources DOAJ
author Paola Piva de Freitas
César Galusni Senna
Mayara Tabai
Carlos Takahiro Chone
Albina Altemani
spellingShingle Paola Piva de Freitas
César Galusni Senna
Mayara Tabai
Carlos Takahiro Chone
Albina Altemani
Metastatic Basal Cell Carcinoma: A Rare Manifestation of a Common Disease
Case Reports in Medicine
author_facet Paola Piva de Freitas
César Galusni Senna
Mayara Tabai
Carlos Takahiro Chone
Albina Altemani
author_sort Paola Piva de Freitas
title Metastatic Basal Cell Carcinoma: A Rare Manifestation of a Common Disease
title_short Metastatic Basal Cell Carcinoma: A Rare Manifestation of a Common Disease
title_full Metastatic Basal Cell Carcinoma: A Rare Manifestation of a Common Disease
title_fullStr Metastatic Basal Cell Carcinoma: A Rare Manifestation of a Common Disease
title_full_unstemmed Metastatic Basal Cell Carcinoma: A Rare Manifestation of a Common Disease
title_sort metastatic basal cell carcinoma: a rare manifestation of a common disease
publisher Hindawi Limited
series Case Reports in Medicine
issn 1687-9627
1687-9635
publishDate 2017-01-01
description Introduction. Basal cell carcinoma (BCC) is considered the most common malignancy in Caucasians. It constituted about 80% of all nonmelanoma skin tumors and, despite its high prevalence, is an extremely rare occurrence of metastases, with incidence rates varying from 0.0028% to 0.55%. Case Report. A 58-year-old male patient with BCC on the left nasolabial sulcus for 17 years, reporting 3 previous excisions, evolved with local recurrence. A new procedure was performed, and anatomopathological study confirmed sclerosing BCC. Seven months later, he presented with a mass in the left submandibular region. Combined positron-emission tomography and computed tomography (PET-CT) showed cervical hypercaptation in the left cervical level I and vertebral body of L5. Excision of the cervical lesion was performed with diagnosis of sclerosing BCC compromising the submandibular gland. Biopsy of the lumbar lesion was found to be compatible with bone metastasis. Conclusion. BCC represents a very common entity, and the presence of metastasis, although infrequent, must be proposed because of the greater morbidity and mortality of this complication. This case shows the importance of early diagnosis and intervention in BCC as a way to avoid unfavorable outcomes.
url http://dx.doi.org/10.1155/2017/8929745
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