Case Report: Primary dural based diffuse large B-Cell lymphoma in a 14 year-old boy [v1; ref status: indexed, http://f1000r.es/56s]

• Main Authors: Sunil Munakomi, Binod Bhattarai, Balaji Srinivas, Iype Cherian
• Format: Article
• Language: English
• Published: F1000 Research Ltd 2015-03-01
• Series: F1000Research
• Subjects: Cancer Therapeutics; Head & Neck Cancers; Lymphomas & Myelomas; Neurobiology of Disease & Regeneration; Pediatric Oncology
• Online Access: http://f1000research.com/articles/4-78/v1

Primary dural lymphoma is a subentity of primary leptomeningeal lymphoma which represents 0.1% of all non-Hodgkin’s lymphomas. Only five cases have been reported so far. We report a very rare case of primary dural-based lymphoma in a 14 year-old boy presenting with mass effect. The patient was managed with excision of the lesion and removal of the involved bone. Post-operatively, the patient showed good recovery. He was then referred to the oncology unit for further chemo- and radiation therapy. A high index of suspicion should therefore be kept in order to diagnose the condition in a timely fashion and then plan for appropriate management since diffuse large cell lymphoma has a relatively benign clinical prognosis.