Reduced Plasma Dopamine-β-Hydroxylase Activity Is Associated With the Severity of Bipolar Disorder: A Pilot Study

Reduced Plasma Dopamine-β-Hydroxylase Activity Is Associated With the Severity of Bipolar Disorder: A Pilot Study

Dopamine-β-hydroxylase (DβH) is an enzyme converting dopamine to norepinephrine, a key neurotransmitter in mood disorders, such as major depressive disorder (MDD) and bipolar disorder (BD). Due to overlapping symptomology of unipolar and bipolar depression, the present study attempted to explorer if...

Full description

Bibliographic Details
Main Authors:	Zuoli Sun, Qijing Bo, Zhen Mao, Feng Li, Fan He, Christine Pao, Wenbiao Li, Yi He, Xin Ma, Chuanyue Wang
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2021-04-01
Series:	Frontiers in Psychiatry
Subjects:	dopamine-β-hydroxylase bipolar disorder major depressive disorder mood disorder cognitive function
Online Access:	https://www.frontiersin.org/articles/10.3389/fpsyt.2021.566091/full

Similar Items

Prepulse inhibition in patients with bipolar disorder: a systematic review and meta-analysis
by: Zhen Mao, et al.
Published: (2019-09-01)

The reliability and validity of PHQ-9 in patients with major depressive disorder in psychiatric hospital
by: Yue Sun, et al.
Published: (2020-09-01)

Novel Mutations in the Tyrosine Hydroxylase Gene in the First Czech Patient with Tyrosine Hydroxylase Deficiency
by: K. Szentiványi, et al.
Published: (2012-01-01)

Involvement of tryptophan hydroxylase 2 gene polymorphisms in susceptibility to tic disorder in Chinese Han population
by: Zheng Ping, et al.
Published: (2013-01-01)

Mutations in the gene of lysyl hydroxylase of patients with Ehlers-Danlos syndrome type VI
by: Pousi, B. (Birgitta)
Published: (1999)

Brain-Specific Oxysterols and Risk of Schizophrenia in Clinical High-Risk Subjects and Patients With Schizophrenia
by: Zuoli Sun, et al.
Published: (2021-08-01)

Use of the MATRICS consensus cognitive battery (MCCB) to evaluate cognitive deficits in bipolar disorder: A systematic review and meta-analysis.
by: Qijing Bo, et al.
Published: (2017-01-01)

Personality disorders in euthymic bipolar patients: a systematic review
by: Severino Bezerra-Filho, et al.
Published: (2015-06-01)

Changes in Non-Coding RNA in Depression and Bipolar Disorder: Can They Be Used as Diagnostic or Theranostic Biomarkers?
by: Andrew Gibbons, et al.
Published: (2020-08-01)

Co-morbidity in bipolar disorder: A retrospective study
by: Ravindra Neelakanthappa Munoli, et al.
Published: (2014-01-01)

Suicide attempts in bipolar I patients: impact of comorbid personality disorders
by: Severino Bezerra Filho, et al.

Comparison of stigmatizing experiences between Korean and Canadian patients with depression and bipolar disorders
by: LEE, HYEWON
Published: (2012)

Repetitive transcranial magnetic stimulation induced hypomanic symptoms in a woman with a history of electroconvulsive therapy induced mania: a case report [v1; ref status: indexed, http://f1000r.es/2kl]
by: Noah S. Philip, et al.
Published: (2013-12-01)

Normalizing sleep quality disturbed by psychiatric polypharmacy: a single patient open trial (SPOT) [version 2; referees: 2 approved]
by: Victoria Magnuson, et al.
Published: (2016-09-01)

Emotional impairment in Parkinson's disease
by: Shu-hua LI, et al.
Published: (2013-08-01)

Envy's pathology: Historical contexts [version 2; referees: 2 approved]
by: Lina Minou
Published: (2017-05-01)

Suicide Risk in Bipolar Disorder: A Brief Review
by: Peter Dome, et al.
Published: (2019-07-01)

CACNA1C Risk Variant and Mood Stabilizers Effects in the Prefrontal Cortical Thickness of Mexican Patients with Bipolar Disorder
by: Rodríguez-Ramírez AM, et al.
Published: (2020-05-01)

Systematic Review of Epigenetic Effects of Pharmacological Agents for Bipolar Disorders
by: Laura E. Lockwood, et al.
Published: (2017-11-01)

An improved assay procedure for dopamine-B-hydroxylase
by: Holubitsky, Don J.
Published: (2010)

Altered functional connectivity in posttraumatic stress disorder with versus without comorbid major depressive disorder: a resting state fMRI study [v2; ref status: indexed, http://f1000r.es/398]
by: Mitzy Kennis, et al.
Published: (2014-04-01)

A study on prevalence of psychiatric morbidity and substance abuse among prisoners
by: Suryanarayana Raju Tirumani, et al.
Published: (2020-08-01)

Exploration of life events and perceived stress in female patients admitted in the psychiatry department of a tertiary care hospital
by: Lakshmi Borgohain, et al.
Published: (2020-08-01)

Mindfulness in mood and anxiety disorders: a review of the literature
by: Michele F. Rodrigues, et al.
Published: (2017-07-01)

Diagnosis of female 17α-hydroxylase deficiency after gonadectomy: a case report
by: Yukiko Mikami, et al.
Published: (2019-07-01)

Evaluation of Cerebral Cortex Function in Clients with Bipolar Mood Disorder I (BMD I) Compared With BMD II Using QEEG Analysis
by: Ali Khaleghi, et al.
Published: (2016-02-01)

Barriers and facilitators perceived by people with bipolar disorder for the practice of exercise: a qualitative study
by: Caroline Silveira Pereira, et al.
Published: (2019-04-01)

Epigenetic Studies of Bipolar Disorder
by: Jeremian, Richie
Published: (2014)

Epigenetic Studies of Bipolar Disorder
by: Jeremian, Richie
Published: (2014)

Anatomical and neurochemical mechanisms of apathy in Parkinson's disease
by: Hao-tian WANG, et al.
Published: (2018-10-01)

Nightmares in Patients with Major Depressive Disorder, Bipolar Disorder, and Psychotic Disorders: A Systematic Review
by: Marine Ambar Akkaoui, et al.
Published: (2020-12-01)

Quetiapine fumarate augmentation for patients with a primary anxiety disorder or a mood disorder: a pilot study
by: Chen Yi-Chih, et al.
Published: (2012-09-01)

Distant mood monitoring for depressive and bipolar disorders: a systematic review
by: A. S. J. van der Watt, et al.
Published: (2020-07-01)

Genealogy study of three generations of patients with bipolar mood disorder Type I
by: Bahman Salehi, et al.
Published: (2017-01-01)

Hypnotic drug risks of mortality, infection, depression, and cancer: but lack of benefit [version 1; referees: 2 approved]
by: Daniel F. Kripke
Published: (2016-05-01)

The Association Between Ginseng and Mania: A Case Report and Literature Review
by: Robabeh Soleimani, et al.
Published: (2020-03-01)

Hypnotic drug risks of mortality, infection, depression, and cancer: but lack of benefit [version 3; referees: 2 approved]
by: Daniel F. Kripke
Published: (2018-11-01)

Hypnotic drug risks of mortality, infection, depression, and cancer: but lack of benefit [version 2; referees: 2 approved]
by: Daniel F. Kripke
Published: (2017-03-01)

Participants’ perspectives of weekly telephonic mood monitoring in South Africa: a feasibility study
by: A. S. J. Van der Watt, et al.
Published: (2018-02-01)

Cardiovascular risk profile of adults with psychotic disorders in Eldoret, Kenya
by: Kwobah, Edith Wanjiku Kamaru
Published: (2021)