Non-coding RNAs are involved in the response to oxidative stress
Oxidative stress is resulted from the imbalance between the production of oxidative agents and the antioxidant capacity. The accumulation of reactive oxygen species in this process leads to induction of several pathologic events in the tissues and organs which might affect the whole organism. This p...
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doaj-b03059dbf2574f5a94a650f4561988852021-05-20T07:41:57ZengElsevierBiomedicine & Pharmacotherapy0753-33222020-07-01127110228Non-coding RNAs are involved in the response to oxidative stressSoudeh Ghafouri-Fard0Hamed Shoorei1Mohammad Taheri2Department of Medical Genetics, Shahid Beheshti University of Medical Sciences, Tehran, IranDepartment of Anatomical Sciences, Faculty of Medicine, Birjand University of Medical Sciences, Birjand, IranUrogenital Stem Cell Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran; Corresponding author.Oxidative stress is resulted from the imbalance between the production of oxidative agents and the antioxidant capacity. The accumulation of reactive oxygen species in this process leads to induction of several pathologic events in the tissues and organs which might affect the whole organism. This process is involved in the pathogenesis of several human disorders. Recent studies have shown the role of non-coding RNAs including both microRNAs (miRNAs) and long non-coding RNAs (lncRNAs) in the pathogenic process of oxidative stress and the response of cells to this process. Thus, regulating expression of these transcripts can be a practical route for modulation of oxidative stress. Moreover, these transcripts can be regarded as biomarkers for assessment of the levels of oxidative/ antioxidative imbalance. In the present review, we summarize the up-to-date literature about the role of lncRNAs and miRNAs in the oxidative stress.http://www.sciencedirect.com/science/article/pii/S0753332220304200Oxidative stresslncRNAmiRNA |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Soudeh Ghafouri-Fard Hamed Shoorei Mohammad Taheri |
spellingShingle |
Soudeh Ghafouri-Fard Hamed Shoorei Mohammad Taheri Non-coding RNAs are involved in the response to oxidative stress Biomedicine & Pharmacotherapy Oxidative stress lncRNA miRNA |
author_facet |
Soudeh Ghafouri-Fard Hamed Shoorei Mohammad Taheri |
author_sort |
Soudeh Ghafouri-Fard |
title |
Non-coding RNAs are involved in the response to oxidative stress |
title_short |
Non-coding RNAs are involved in the response to oxidative stress |
title_full |
Non-coding RNAs are involved in the response to oxidative stress |
title_fullStr |
Non-coding RNAs are involved in the response to oxidative stress |
title_full_unstemmed |
Non-coding RNAs are involved in the response to oxidative stress |
title_sort |
non-coding rnas are involved in the response to oxidative stress |
publisher |
Elsevier |
series |
Biomedicine & Pharmacotherapy |
issn |
0753-3322 |
publishDate |
2020-07-01 |
description |
Oxidative stress is resulted from the imbalance between the production of oxidative agents and the antioxidant capacity. The accumulation of reactive oxygen species in this process leads to induction of several pathologic events in the tissues and organs which might affect the whole organism. This process is involved in the pathogenesis of several human disorders. Recent studies have shown the role of non-coding RNAs including both microRNAs (miRNAs) and long non-coding RNAs (lncRNAs) in the pathogenic process of oxidative stress and the response of cells to this process. Thus, regulating expression of these transcripts can be a practical route for modulation of oxidative stress. Moreover, these transcripts can be regarded as biomarkers for assessment of the levels of oxidative/ antioxidative imbalance. In the present review, we summarize the up-to-date literature about the role of lncRNAs and miRNAs in the oxidative stress. |
topic |
Oxidative stress lncRNA miRNA |
url |
http://www.sciencedirect.com/science/article/pii/S0753332220304200 |
work_keys_str_mv |
AT soudehghafourifard noncodingrnasareinvolvedintheresponsetooxidativestress AT hamedshoorei noncodingrnasareinvolvedintheresponsetooxidativestress AT mohammadtaheri noncodingrnasareinvolvedintheresponsetooxidativestress |
_version_ |
1721435023050014720 |