Locomotor analysis identifies early compensatory changes during disease progression and subgroup classification in a mouse model of amyotrophic lateral sclerosis

Locomotor analysis identifies early compensatory changes during disease progression and subgroup classification in a mouse model of amyotrophic lateral sclerosis

Amyotrophic lateral sclerosis is a motoneuron degenerative disease that is challenging to diagnose and presents with considerable variability in survival. Early identification and enhanced understanding of symptomatic patterns could aid in diagnosis and provide an avenue for monitoring disease progr...

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Bibliographic Details
Main Authors: Melissa M Haulcomb, Rena M Meadows, Whitney M Miller, Kathryn P McMillan, MeKenzie J Hilsmeyer, Xuefu Wang, Wesley T Beaulieu, Stephanie L Dickinson, Todd J Brown, Virginia M Sanders, Kathryn J Jones
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2017-01-01
Series:Neural Regeneration Research
Subjects:
nerve regeneration; amyotrophic lateral sclerosis; motoneuron degenerative disease; locomotor; disease progression; disease variability; SOD1 mouse; neural regeneration
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2017;volume=12;issue=10;spage=1664;epage=1679;aulast=

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