A Natural Meliorate: Revolutionary Tissue Engineering in Endodontics

• Main Authors: I.B. Geeta, Girish Galagali, Kulkarni Sangeeta, Suran Pushpa, Faizal Noushin
• Format: Article
• Language: English
• Published: JCDR Research and Publications Private Limited 2013-11-01
• Series: Journal of Clinical and Diagnostic Research
• Subjects: platelet rich fibrin; apexification; pulpotomy; tissue engineering
• Online Access: https://jcdr.net/articles/PDF/3638/70-%206915_E(%20_%20)_F(H)_PF1(VH)_PFA(P)_PF2(PP)_U(PP).pdf

Platelet-Rich Fibrin (PRF) was first described by Choukroun et al., (2001). It has been referred to as a second-generation platelet concentrate, which has been shown to have several advantages over traditionally prepared platelet-rich plasma. PRF has a physiologic architecture that is very favourable to the healing process, obtained due to the slow polymerization process. The development of platelet concentrate as bioactive surgical additives that are applied locally to promote wound healing stems from the use of fibrin adhesive. Developments in the field of tissue engineering have made the generation of artificial substitutes in several areas of medicine. Various clinical applications in endodontics include Periapical surgeries, Revascularisationprocedures, Regenerative pulpotomy, Perforation repair. This article aims to discuss the various applications of PRF in the field of Endodontics with few case reports.