Impaired hippocampal neurogenesis is involved in cognitive dysfunction induced by thiamine deficiency at early pre-pathological lesion stage

Impaired hippocampal neurogenesis is involved in cognitive dysfunction induced by thiamine deficiency at early pre-pathological lesion stage

It has not been reported whether thiamine deficiency (TD) affects hippocampal neurogenesis or not. Here, we explored the influence of TD at early pre-pathological lesion stage on hippocampal neurogenesis and the correlation between affected hippocampal neurogenesis and cognitive dysfunction. We prep...

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Bibliographic Details
Main Authors: Na Zhao, Chunjiu Zhong, Yang Wang, Yanling Zhao, Neng Gong, Guomin Zhou, Tianle Xu, Zhen Hong
Format: Article
Language:English
Published: Elsevier 2008-02-01
Series:Neurobiology of Disease
Subjects:
Thiamine deficiency
Learning and memory
Hippocampal neurogenesis
Mouse
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996107001969

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