Greater macrovascular and microvascular morbidity from type 2 diabetes in northern compared with southern China: A cross‐sectional study
Abstract Aims/Introduction There are substantial differences in genes, diet, culture and environment between the northern and southern Chinese populations, which might influence treatment strategy and screening policy. We studied the differences in type 2 diabetes and diabetic complications between...
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doaj-b08a86c2715b4f4ea3ae6bd9cb1c8d222021-05-02T20:20:02ZengWileyJournal of Diabetes Investigation2040-11162040-11242020-09-011151285129410.1111/jdi.13262Greater macrovascular and microvascular morbidity from type 2 diabetes in northern compared with southern China: A cross‐sectional studyLi Wang0Ying Xing1Xinwen Yu2Jie Ming3Xiangyang Liu4Xiaomiao Li5Jianfang Fu6Jie Zhou7Bin Gao8Dayi Hu9Changyu Pan10Linong Ji11Qiuhe Ji12Department of Endocrinology and Metabolism Xijing Hospital Xi’an, Shaanxi ChinaDepartment of Endocrinology and Metabolism Xijing Hospital Xi’an, Shaanxi ChinaDepartment of Endocrinology and Metabolism Xijing Hospital Xi’an, Shaanxi ChinaDepartment of Endocrinology and Metabolism Xijing Hospital Xi’an, Shaanxi ChinaDepartment of Endocrinology and Metabolism Xijing Hospital Xi’an, Shaanxi ChinaDepartment of Endocrinology and Metabolism Xijing Hospital Xi’an, Shaanxi ChinaDepartment of Endocrinology and Metabolism Xijing Hospital Xi’an, Shaanxi ChinaDepartment of Endocrinology and Metabolism Xijing Hospital Xi’an, Shaanxi ChinaDepartment of Endocrinology and Metabolism Xijing Hospital Xi’an, Shaanxi ChinaDepartment of Cardiology Peking University People’s Hospital Beijing ChinaDepartment of Endocrinology Beijing 301 Military General Hospital Beijing ChinaDepartment of Endocrinology and Metabolism Peking University People’s Hospital Beijing ChinaDepartment of Endocrinology and Metabolism Xijing Hospital Xi’an, Shaanxi ChinaAbstract Aims/Introduction There are substantial differences in genes, diet, culture and environment between the northern and southern Chinese populations, which might influence treatment strategy and screening policy. We studied the differences in type 2 diabetes and diabetic complications between northern and southern China. Materials and Methods We carried out a cross‐sectional survey using data from the China Cardiometabolic Registries on blood pressure, blood lipids and blood glucose in 25,398 Chinese type 2 diabetes patients. Macrovascular, microvascular and other complications were collected by self‐report or medical records, and then divided into the northern and southern groups by the boundary of the Yangtze River. Results Northern patients were younger, and had heavier weight, greater body mass index and waist circumference, higher blood pressure, higher total cholesterol, higher low‐density lipoprotein cholesterol, and higher hemoglobin A1C. The prevalence of cardiovascular, cerebrovascular and macrovascular complications were 1.76‐fold, 1.24‐fold and 1.47‐fold more in northern than that in southern Chinese patients. In addition, the prevalence of diabetic nephropathy, retinopathy, neuropathy and microvascular complications in northern Chinese patients also increased. When stratified by age, the difference in both cardiovascular disease and ischemic stroke morbidity became significant, even in the 35–44 years age group. Conclusions More macrovascular and microvascular complications were found in northern compared with southern patients, and the largest difference also appeared in the younger age groups <55 years, which might be meaningful to a screening and treatment strategy according to geographic differences.https://doi.org/10.1111/jdi.13262Macrovascular complicationMicrovascular complicationType 2 diabetes |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Li Wang Ying Xing Xinwen Yu Jie Ming Xiangyang Liu Xiaomiao Li Jianfang Fu Jie Zhou Bin Gao Dayi Hu Changyu Pan Linong Ji Qiuhe Ji |
spellingShingle |
Li Wang Ying Xing Xinwen Yu Jie Ming Xiangyang Liu Xiaomiao Li Jianfang Fu Jie Zhou Bin Gao Dayi Hu Changyu Pan Linong Ji Qiuhe Ji Greater macrovascular and microvascular morbidity from type 2 diabetes in northern compared with southern China: A cross‐sectional study Journal of Diabetes Investigation Macrovascular complication Microvascular complication Type 2 diabetes |
author_facet |
Li Wang Ying Xing Xinwen Yu Jie Ming Xiangyang Liu Xiaomiao Li Jianfang Fu Jie Zhou Bin Gao Dayi Hu Changyu Pan Linong Ji Qiuhe Ji |
author_sort |
Li Wang |
title |
Greater macrovascular and microvascular morbidity from type 2 diabetes in northern compared with southern China: A cross‐sectional study |
title_short |
Greater macrovascular and microvascular morbidity from type 2 diabetes in northern compared with southern China: A cross‐sectional study |
title_full |
Greater macrovascular and microvascular morbidity from type 2 diabetes in northern compared with southern China: A cross‐sectional study |
title_fullStr |
Greater macrovascular and microvascular morbidity from type 2 diabetes in northern compared with southern China: A cross‐sectional study |
title_full_unstemmed |
Greater macrovascular and microvascular morbidity from type 2 diabetes in northern compared with southern China: A cross‐sectional study |
title_sort |
greater macrovascular and microvascular morbidity from type 2 diabetes in northern compared with southern china: a cross‐sectional study |
publisher |
Wiley |
series |
Journal of Diabetes Investigation |
issn |
2040-1116 2040-1124 |
publishDate |
2020-09-01 |
description |
Abstract Aims/Introduction There are substantial differences in genes, diet, culture and environment between the northern and southern Chinese populations, which might influence treatment strategy and screening policy. We studied the differences in type 2 diabetes and diabetic complications between northern and southern China. Materials and Methods We carried out a cross‐sectional survey using data from the China Cardiometabolic Registries on blood pressure, blood lipids and blood glucose in 25,398 Chinese type 2 diabetes patients. Macrovascular, microvascular and other complications were collected by self‐report or medical records, and then divided into the northern and southern groups by the boundary of the Yangtze River. Results Northern patients were younger, and had heavier weight, greater body mass index and waist circumference, higher blood pressure, higher total cholesterol, higher low‐density lipoprotein cholesterol, and higher hemoglobin A1C. The prevalence of cardiovascular, cerebrovascular and macrovascular complications were 1.76‐fold, 1.24‐fold and 1.47‐fold more in northern than that in southern Chinese patients. In addition, the prevalence of diabetic nephropathy, retinopathy, neuropathy and microvascular complications in northern Chinese patients also increased. When stratified by age, the difference in both cardiovascular disease and ischemic stroke morbidity became significant, even in the 35–44 years age group. Conclusions More macrovascular and microvascular complications were found in northern compared with southern patients, and the largest difference also appeared in the younger age groups <55 years, which might be meaningful to a screening and treatment strategy according to geographic differences. |
topic |
Macrovascular complication Microvascular complication Type 2 diabetes |
url |
https://doi.org/10.1111/jdi.13262 |
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