Melatonin and Sleep-Wake Rhythms before and after Ocular Lens Replacement in Elderly Humans
Light of short wavelengths has been shown to play a key role in non-image forming responses. Due to aging, the ocular lens becomes more yellow reducing the transmission of short wavelengths in the elderly. In the present study, we make use of cataract surgery to investigate the effects of a relative...
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doaj-b08d8ba37c9b4e59b139a7a03f13b38b2020-11-24T22:33:51ZengMDPI AGBiology2079-77372016-02-01511210.3390/biology5010012biology5010012Melatonin and Sleep-Wake Rhythms before and after Ocular Lens Replacement in Elderly HumansMarina Giménez0Domien Beersma1Serge Daan2Bert van der Pol3Martijn Kanis4Dick van Norren5Marijke Gordijn6Department of Chronobiology, GeLifes, University of Groningen, Groningen 9747 AG, The NetherlandsDepartment of Chronobiology, GeLifes, University of Groningen, Groningen 9747 AG, The NetherlandsDepartment of Chronobiology, GeLifes, University of Groningen, Groningen 9747 AG, The NetherlandsDepartment of Ophthalmology, University Medical Centre Groningen, Groningen 9713 GZ, The NetherlandsDepartment of Ophthalmology, University Medical Centre Utrecht, Utrecht 3584 CX, The NetherlandsDepartment of Ophthalmology, University Medical Centre Utrecht, Utrecht 3584 CX, The NetherlandsDepartment of Chronobiology, GeLifes, University of Groningen, Groningen 9747 AG, The NetherlandsLight of short wavelengths has been shown to play a key role in non-image forming responses. Due to aging, the ocular lens becomes more yellow reducing the transmission of short wavelengths in the elderly. In the present study, we make use of cataract surgery to investigate the effects of a relative increase of short wavelength transmission on melatonin- and sleep-wake rhythms (N = 14). We observed, on average, a delay of the sleep-wake and the nocturnal melatonin rhythms after cataract surgery. This delay is tentatively attributed to a relatively large increase of light transmittance in the evening hours more than an increase of the already relatively high light intensities found in the daytime. The later phase that we observed after cataract surgery (clear lens) as compared to the earlier phase observed before cataract (yellowish lens) is in agreement with the general later phase reported in the young (clear lens) population.http://www.mdpi.com/2079-7737/5/1/12agingocular lenscataract surgerysleep-wake rhythmsmelatonin rhythmshumans |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Marina Giménez Domien Beersma Serge Daan Bert van der Pol Martijn Kanis Dick van Norren Marijke Gordijn |
spellingShingle |
Marina Giménez Domien Beersma Serge Daan Bert van der Pol Martijn Kanis Dick van Norren Marijke Gordijn Melatonin and Sleep-Wake Rhythms before and after Ocular Lens Replacement in Elderly Humans Biology aging ocular lens cataract surgery sleep-wake rhythms melatonin rhythms humans |
author_facet |
Marina Giménez Domien Beersma Serge Daan Bert van der Pol Martijn Kanis Dick van Norren Marijke Gordijn |
author_sort |
Marina Giménez |
title |
Melatonin and Sleep-Wake Rhythms before and after Ocular Lens Replacement in Elderly Humans |
title_short |
Melatonin and Sleep-Wake Rhythms before and after Ocular Lens Replacement in Elderly Humans |
title_full |
Melatonin and Sleep-Wake Rhythms before and after Ocular Lens Replacement in Elderly Humans |
title_fullStr |
Melatonin and Sleep-Wake Rhythms before and after Ocular Lens Replacement in Elderly Humans |
title_full_unstemmed |
Melatonin and Sleep-Wake Rhythms before and after Ocular Lens Replacement in Elderly Humans |
title_sort |
melatonin and sleep-wake rhythms before and after ocular lens replacement in elderly humans |
publisher |
MDPI AG |
series |
Biology |
issn |
2079-7737 |
publishDate |
2016-02-01 |
description |
Light of short wavelengths has been shown to play a key role in non-image forming responses. Due to aging, the ocular lens becomes more yellow reducing the transmission of short wavelengths in the elderly. In the present study, we make use of cataract surgery to investigate the effects of a relative increase of short wavelength transmission on melatonin- and sleep-wake rhythms (N = 14). We observed, on average, a delay of the sleep-wake and the nocturnal melatonin rhythms after cataract surgery. This delay is tentatively attributed to a relatively large increase of light transmittance in the evening hours more than an increase of the already relatively high light intensities found in the daytime. The later phase that we observed after cataract surgery (clear lens) as compared to the earlier phase observed before cataract (yellowish lens) is in agreement with the general later phase reported in the young (clear lens) population. |
topic |
aging ocular lens cataract surgery sleep-wake rhythms melatonin rhythms humans |
url |
http://www.mdpi.com/2079-7737/5/1/12 |
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