Elevated GDNF levels following viral vector-mediated gene transfer can increase neuronal death after stroke in rats

Previous studies have indicated that administration of glial cell line-derived neurotrophic factor (GDNF) counteracts neuronal death after stroke. However, in these studies damage was evaluated at most a few days after the insult. Here, we have explored the long-term consequences of two routes of GD...

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Bibliographic Details
Main Authors: Andreas Arvidsson, Deniz Kirik, Cecilia Lundberg, Ronald J Mandel, Gunnar Andsberg, Zaal Kokaia, Olle Lindvall
Format: Article
Language:English
Published: Elsevier 2003-12-01
Series:Neurobiology of Disease
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996103001542