Effects of host restriction factors and the HTLV-1 subtype on susceptibility to HTLV-1-associated myelopathy/tropical spastic paraparesis

Effects of host restriction factors and the HTLV-1 subtype on susceptibility to HTLV-1-associated myelopathy/tropical spastic paraparesis

Abstract Background Although human T-lymphotropic virus type 1 (HTLV-1) infection is a prerequisite for the development of HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP), specific provirus mutations in HAM/TSP have not yet been reported. In this study, we examined whether HAM/TS...

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Bibliographic Details
Main Authors: Satoshi Nozuma, Eiji Matsuura, Daisuke Kodama, Yuichi Tashiro, Toshio Matsuzaki, Ryuji Kubota, Shuji Izumo, Hiroshi Takashima
Format: Article
Language:English
Published: BMC 2017-04-01
Series:Retrovirology
Subjects:
HTLV-1
HAM/TSP
Transcontinental subtype
TRIM5α
Online Access:http://link.springer.com/article/10.1186/s12977-017-0350-9

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