Intracellular <i>S. aureus</i> in Osteoblasts in a Clinical Sample from a Patient with Chronic Osteomyelitis—A Case Report

The pathophysiological role of intracellular bacteria in osteomyelitis is still a matter of debate. Here, we demonstrate for the first time the presence of <i>Staphylococcus aureus</i> internalized into osteoblasts in human tissue samples of a case with a chronic osteomyelitis using ultr...

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Main Authors:	Nike Walter, Daniel Mendelsohn, Christoph Brochhausen, Markus Rupp, Volker Alt
Format:	Article
Language:	English
Published:	MDPI AG 2021-08-01
Series:	Pathogens
Subjects:	osteomyelitis intracellular <i>S. aureus</i> osteoblast ultrastructural analysis
Online Access:	https://www.mdpi.com/2076-0817/10/8/1064

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spelling	doaj-b0abc7782f284316871f74e19d7dbf5c2021-08-26T14:11:59ZengMDPI AGPathogens2076-08172021-08-01101064106410.3390/pathogens10081064Intracellular <i>S. aureus</i> in Osteoblasts in a Clinical Sample from a Patient with Chronic Osteomyelitis—A Case ReportNike Walter0Daniel Mendelsohn1Christoph Brochhausen2Markus Rupp3Volker Alt4Department for Trauma Surgery, University Hospital Regensburg, 93053 Regensburg, GermanyDepartment for Trauma Surgery, University Hospital Regensburg, 93053 Regensburg, GermanyInstitute of Pathology, University Hospital Regensburg, 93053 Regensburg, GermanyDepartment for Trauma Surgery, University Hospital Regensburg, 93053 Regensburg, GermanyDepartment for Trauma Surgery, University Hospital Regensburg, 93053 Regensburg, GermanyThe pathophysiological role of intracellular bacteria in osteomyelitis is still a matter of debate. Here, we demonstrate for the first time the presence of <i>Staphylococcus aureus</i> internalized into osteoblasts in human tissue samples of a case with a chronic osteomyelitis using ultrastructural transmission electron microscope analysis.https://www.mdpi.com/2076-0817/10/8/1064osteomyelitisintracellular <i>S. aureus</i>osteoblastultrastructural analysis
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Nike Walter Daniel Mendelsohn Christoph Brochhausen Markus Rupp Volker Alt
spellingShingle	Nike Walter Daniel Mendelsohn Christoph Brochhausen Markus Rupp Volker Alt Intracellular <i>S. aureus</i> in Osteoblasts in a Clinical Sample from a Patient with Chronic Osteomyelitis—A Case Report Pathogens osteomyelitis intracellular <i>S. aureus</i> osteoblast ultrastructural analysis
author_facet	Nike Walter Daniel Mendelsohn Christoph Brochhausen Markus Rupp Volker Alt
author_sort	Nike Walter
title	Intracellular <i>S. aureus</i> in Osteoblasts in a Clinical Sample from a Patient with Chronic Osteomyelitis—A Case Report
title_short	Intracellular <i>S. aureus</i> in Osteoblasts in a Clinical Sample from a Patient with Chronic Osteomyelitis—A Case Report
title_full	Intracellular <i>S. aureus</i> in Osteoblasts in a Clinical Sample from a Patient with Chronic Osteomyelitis—A Case Report
title_fullStr	Intracellular <i>S. aureus</i> in Osteoblasts in a Clinical Sample from a Patient with Chronic Osteomyelitis—A Case Report
title_full_unstemmed	Intracellular <i>S. aureus</i> in Osteoblasts in a Clinical Sample from a Patient with Chronic Osteomyelitis—A Case Report
title_sort	intracellular <i>s. aureus</i> in osteoblasts in a clinical sample from a patient with chronic osteomyelitis—a case report
publisher	MDPI AG
series	Pathogens
issn	2076-0817
publishDate	2021-08-01
description	The pathophysiological role of intracellular bacteria in osteomyelitis is still a matter of debate. Here, we demonstrate for the first time the presence of <i>Staphylococcus aureus</i> internalized into osteoblasts in human tissue samples of a case with a chronic osteomyelitis using ultrastructural transmission electron microscope analysis.
topic	osteomyelitis intracellular <i>S. aureus</i> osteoblast ultrastructural analysis
url	https://www.mdpi.com/2076-0817/10/8/1064
work_keys_str_mv	AT nikewalter intracellularisaureusiinosteoblastsinaclinicalsamplefromapatientwithchronicosteomyelitisacasereport AT danielmendelsohn intracellularisaureusiinosteoblastsinaclinicalsamplefromapatientwithchronicosteomyelitisacasereport AT christophbrochhausen intracellularisaureusiinosteoblastsinaclinicalsamplefromapatientwithchronicosteomyelitisacasereport AT markusrupp intracellularisaureusiinosteoblastsinaclinicalsamplefromapatientwithchronicosteomyelitisacasereport AT volkeralt intracellularisaureusiinosteoblastsinaclinicalsamplefromapatientwithchronicosteomyelitisacasereport
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Intracellular <i>S. aureus</i> in Osteoblasts in a Clinical Sample from a Patient with Chronic Osteomyelitis—A Case Report

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