The Pattern and Function of DNA Methylation in Fungal Plant Pathogens
To successfully infect plants and trigger disease, fungal plant pathogens use various strategies that are dependent on characteristics of their biology and genomes. Although pathogenic fungi are different from animals and plants in the genomic heritability, sequence feature, and epigenetic modificat...
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doaj-b0daf1e7a7dd40fcb7fc4c56a3fc403e2020-11-25T02:33:37ZengMDPI AGMicroorganisms2076-26072020-02-018222710.3390/microorganisms8020227microorganisms8020227The Pattern and Function of DNA Methylation in Fungal Plant PathogensChang He0Zhanquan Zhang1Boqiang Li2Shiping Tian3Key Laboratory of Plant Resources, Institute of Botany, Chinese Academy of Sciences, Beijing 100093, ChinaKey Laboratory of Plant Resources, Institute of Botany, Chinese Academy of Sciences, Beijing 100093, ChinaKey Laboratory of Plant Resources, Institute of Botany, Chinese Academy of Sciences, Beijing 100093, ChinaKey Laboratory of Plant Resources, Institute of Botany, Chinese Academy of Sciences, Beijing 100093, ChinaTo successfully infect plants and trigger disease, fungal plant pathogens use various strategies that are dependent on characteristics of their biology and genomes. Although pathogenic fungi are different from animals and plants in the genomic heritability, sequence feature, and epigenetic modification, an increasing number of phytopathogenic fungi have been demonstrated to share DNA methyltransferases (MTases) responsible for DNA methylation with animals and plants. Fungal plant pathogens predominantly possess four types of DNA MTase homologs, including DIM-2, DNMT1, DNMT5, and RID. Numerous studies have indicated that DNA methylation in phytopathogenic fungi mainly distributes in transposable elements (TEs), gene promoter regions, and the repetitive DNA sequences. As an important and heritable epigenetic modification, DNA methylation is associated with silencing of gene expression and transposon, and it is responsible for a wide range of biological phenomena in fungi. This review highlights the relevant reports and insights into the important roles of DNA methylation in the modulation of development, pathogenicity, and secondary metabolism of fungal plant pathogens. Recent evidences prove that there are massive links between DNA and histone methylation in fungi, and they commonly regulate fungal development and mycotoxin biosynthesis.https://www.mdpi.com/2076-2607/8/2/227dna methylationfungal plant pathogendevelopmentpathogenicity |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Chang He Zhanquan Zhang Boqiang Li Shiping Tian |
spellingShingle |
Chang He Zhanquan Zhang Boqiang Li Shiping Tian The Pattern and Function of DNA Methylation in Fungal Plant Pathogens Microorganisms dna methylation fungal plant pathogen development pathogenicity |
author_facet |
Chang He Zhanquan Zhang Boqiang Li Shiping Tian |
author_sort |
Chang He |
title |
The Pattern and Function of DNA Methylation in Fungal Plant Pathogens |
title_short |
The Pattern and Function of DNA Methylation in Fungal Plant Pathogens |
title_full |
The Pattern and Function of DNA Methylation in Fungal Plant Pathogens |
title_fullStr |
The Pattern and Function of DNA Methylation in Fungal Plant Pathogens |
title_full_unstemmed |
The Pattern and Function of DNA Methylation in Fungal Plant Pathogens |
title_sort |
pattern and function of dna methylation in fungal plant pathogens |
publisher |
MDPI AG |
series |
Microorganisms |
issn |
2076-2607 |
publishDate |
2020-02-01 |
description |
To successfully infect plants and trigger disease, fungal plant pathogens use various strategies that are dependent on characteristics of their biology and genomes. Although pathogenic fungi are different from animals and plants in the genomic heritability, sequence feature, and epigenetic modification, an increasing number of phytopathogenic fungi have been demonstrated to share DNA methyltransferases (MTases) responsible for DNA methylation with animals and plants. Fungal plant pathogens predominantly possess four types of DNA MTase homologs, including DIM-2, DNMT1, DNMT5, and RID. Numerous studies have indicated that DNA methylation in phytopathogenic fungi mainly distributes in transposable elements (TEs), gene promoter regions, and the repetitive DNA sequences. As an important and heritable epigenetic modification, DNA methylation is associated with silencing of gene expression and transposon, and it is responsible for a wide range of biological phenomena in fungi. This review highlights the relevant reports and insights into the important roles of DNA methylation in the modulation of development, pathogenicity, and secondary metabolism of fungal plant pathogens. Recent evidences prove that there are massive links between DNA and histone methylation in fungi, and they commonly regulate fungal development and mycotoxin biosynthesis. |
topic |
dna methylation fungal plant pathogen development pathogenicity |
url |
https://www.mdpi.com/2076-2607/8/2/227 |
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