Description of a nanobody-based competitive immunoassay to detect tsetse fly exposure.
BACKGROUND:Tsetse flies are the main vectors of human and animal African trypanosomes. The Tsal proteins in tsetse fly saliva were previously identified as suitable biomarkers of bite exposure. A new competitive assay was conceived based on nanobody (Nb) technology to ameliorate the detection of ant...
Main Authors: | Guy Caljon, Shahid Hussain, Lieve Vermeiren, Jan Van Den Abbeele |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2015-02-01
|
Series: | PLoS Neglected Tropical Diseases |
Online Access: | http://europepmc.org/articles/PMC4320081?pdf=render |
Similar Items
-
Expression and extracellular release of a functional anti-trypanosome Nanobody<sup>® </sup>in <it>Sodalis glossinidius</it>, a bacterial symbiont of the tsetse fly
by: De Vooght Linda, et al.
Published: (2012-02-01) -
The Dermis as a Delivery Site of Trypanosoma brucei for Tsetse Flies.
by: Guy Caljon, et al.
Published: (2016-07-01) -
Identification of a tsetse fly salivary protein with dual inhibitory action on human platelet aggregation.
by: Guy Caljon, et al.
Published: (2010-01-01) -
Serological responses and biomarker evaluation in mice and pigs exposed to tsetse fly bites.
by: Guy Caljon, et al.
Published: (2014-05-01) -
Trypanosoma brucei modifies the tsetse salivary composition, altering the fly feeding behavior that favors parasite transmission.
by: Jan Van Den Abbeele, et al.
Published: (2010-01-01)