Reduced stress-associated FKBP5 DNA methylation together with gut microbiota dysbiosis is linked with the progression of obese PCOS patients

Reduced stress-associated FKBP5 DNA methylation together with gut microbiota dysbiosis is linked with the progression of obese PCOS patients

Abstract Polycystic ovary syndrome (PCOS) is a common endocrine disease in females that is characterized by hyperandrogenemia, chronic anovulation, and polycystic ovaries. However, the exact etiology and pathogenesis of PCOS are still unknown. The aim of this study was to clarify the bacterial, stre...

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Bibliographic Details
Main Authors: Fu Chen, Zhangran Chen, Minjie Chen, Guishan Chen, Qingxia Huang, Xiaoping Yang, Huihuang Yin, Lan Chen, Weichun Zhang, Hong Lin, Miaoqiong Ou, Luanhong Wang, Yongsong Chen, Chujia Lin, Wencan Xu, Guoshu Yin
Format: Article
Language:English
Published: Nature Publishing Group 2021-07-01
Series:npj Biofilms and Microbiomes
Online Access:https://doi.org/10.1038/s41522-021-00231-6

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