Management of nitrobenzene poisoning with oral methylene blue and vitamin C in a resource limited setting: A case report

Management of nitrobenzene poisoning with oral methylene blue and vitamin C in a resource limited setting: A case report

Nitrobenzene can cause life threatening methaemoglobinemia. Its management includes the use of intravenous methylene blue to reduce the iron moiety from its ferric to ferrous state. Due to unavailability of intravenous preparation, enteral methylene blue was used in our case. This case report is to...

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Main Authors: Ninadini Shrestha, Bipin Karki, Pramesh Sunder Shrestha, Rupesh Gami, Subhash Prasad Acharya, Santosh Acharya
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:Toxicology Reports
Subjects:
Methemoglobinemia
Methylene blue
Nitrobenzene
Vitamin C
Online Access:http://www.sciencedirect.com/science/article/pii/S2214750020303747
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spelling doaj-b0f0099f0bcd454784373ec6889ebb8f2020-12-25T05:10:16ZengElsevierToxicology Reports2214-75002020-01-01710081009Management of nitrobenzene poisoning with oral methylene blue and vitamin C in a resource limited setting: A case reportNinadini Shrestha0Bipin Karki1Pramesh Sunder Shrestha2Rupesh Gami3Subhash Prasad Acharya4Santosh Acharya5Department of Anaesthesia, Maharajgunj Medical Campus, Institute of Medicine, GPO Box- 1524, Maharajgunj, Kathmandu, NepalDepartment of Critical Care Medicine, Om Hospital and Research Center Pvt Ltd, GPO Box- 13494, Chabahil, Kathmandu, Nepal; Corresponding author.Department of Anaesthesia, Maharajgunj Medical Campus, Institute of Medicine, GPO Box- 1524, Maharajgunj, Kathmandu, NepalDepartment of Critical Care Medicine, Om Hospital and Research Center Pvt Ltd, GPO Box- 13494, Chabahil, Kathmandu, NepalDepartment of Anaesthesia, Maharajgunj Medical Campus, Institute of Medicine, GPO Box- 1524, Maharajgunj, Kathmandu, NepalDepartment of Critical Care Medicine, Hospital for Advanced Medicine and Surgery, GPO Box- 3832, Dhumbarahi, Kathmandu, NepalNitrobenzene can cause life threatening methaemoglobinemia. Its management includes the use of intravenous methylene blue to reduce the iron moiety from its ferric to ferrous state. Due to unavailability of intravenous preparation, enteral methylene blue was used in our case. This case report is to highlight that even oral preparations can be successfully used in a resource limited setting where often intravenous preparations are unavailable.http://www.sciencedirect.com/science/article/pii/S2214750020303747MethemoglobinemiaMethylene blueNitrobenzeneVitamin C
collection DOAJ
language English
format Article
sources DOAJ
author Ninadini Shrestha
Bipin Karki
Pramesh Sunder Shrestha
Rupesh Gami
Subhash Prasad Acharya
Santosh Acharya
spellingShingle Ninadini Shrestha
Bipin Karki
Pramesh Sunder Shrestha
Rupesh Gami
Subhash Prasad Acharya
Santosh Acharya
Management of nitrobenzene poisoning with oral methylene blue and vitamin C in a resource limited setting: A case report
Toxicology Reports
Methemoglobinemia
Methylene blue
Nitrobenzene
Vitamin C
author_facet Ninadini Shrestha
Bipin Karki
Pramesh Sunder Shrestha
Rupesh Gami
Subhash Prasad Acharya
Santosh Acharya
author_sort Ninadini Shrestha
title Management of nitrobenzene poisoning with oral methylene blue and vitamin C in a resource limited setting: A case report
title_short Management of nitrobenzene poisoning with oral methylene blue and vitamin C in a resource limited setting: A case report
title_full Management of nitrobenzene poisoning with oral methylene blue and vitamin C in a resource limited setting: A case report
title_fullStr Management of nitrobenzene poisoning with oral methylene blue and vitamin C in a resource limited setting: A case report
title_full_unstemmed Management of nitrobenzene poisoning with oral methylene blue and vitamin C in a resource limited setting: A case report
title_sort management of nitrobenzene poisoning with oral methylene blue and vitamin c in a resource limited setting: a case report
publisher Elsevier
series Toxicology Reports
issn 2214-7500
publishDate 2020-01-01
description Nitrobenzene can cause life threatening methaemoglobinemia. Its management includes the use of intravenous methylene blue to reduce the iron moiety from its ferric to ferrous state. Due to unavailability of intravenous preparation, enteral methylene blue was used in our case. This case report is to highlight that even oral preparations can be successfully used in a resource limited setting where often intravenous preparations are unavailable.
topic Methemoglobinemia
Methylene blue
Nitrobenzene
Vitamin C
url http://www.sciencedirect.com/science/article/pii/S2214750020303747
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