Positive regulation of meiotic DNA double-strand break formation by activation of the DNA damage checkpoint kinase Mec1(ATR)
During meiosis, formation and repair of programmed DNA double-strand breaks (DSBs) create genetic exchange between homologous chromosomes—a process that is critical for reductional meiotic chromosome segregation and the production of genetically diverse sexually reproducing populations. Meiotic DSB...
Main Authors: | Stephen Gray, Rachal M. Allison, Valerie Garcia, Alastair S. H. Goldman, Matthew J. Neale |
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Format: | Article |
Language: | English |
Published: |
The Royal Society
2013-01-01
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Series: | Open Biology |
Subjects: | |
Online Access: | https://royalsocietypublishing.org/doi/pdf/10.1098/rsob.130019 |
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