Ovarian morphology after salpingectomy (experimental study)

• Main Authors: I. I. Kupriyanova, I. A. Petrov, O. A. Tikhonovskaya, L. R. Mustafina, A. S. Fateyeva, A. O. Okorokov, S. V. Logvinov
• Format: Article
• Language: English
• Published: Siberian State Medical University (Tomsk) 2016-10-01
• Series: Bûlleten' Sibirskoj Mediciny
• Subjects: salpingectomy; ovarian follicles; morphology.
• Online Access: https://bulletin.tomsk.ru/jour/article/view/667
• ISSN: 1682-0363; 1819-3684

Purpose. To study influence of experimental salpingectomy on morphofunctional state of ovaries in different terms of postoperative period.Materials and methods. The experiment was conducted on mature female rats. The main group consisted of 20 rats with removed oviducts, the control group – 20 intact rats. Rats were euthanized at 2nd, 10th, 30th and 60th days of experiment. Paraffin slides of ovaries were stained with hematoxylin and eosin, and with Van Gieson’s stain. Histological and morphoquantitative investigations were performed.Results. Hemodynamic and exudative disorders, such as leukocyte infiltration focuses in cortex and medulla, stasis of blood cells and leukocytes boundary distance, occur in early terms after bilateral removal of oviducts. On the 2nd day the number of growing follicle increases, most of them have atresia sights. On the 60th day the number of growing follicles decreases and the number of atretic bodies increases. The process of collagen formation enhances.Conclusion. The experimental salpingectomy leads to the deorganization of gonads, interruption of the follicular growing, intensification of atretic processes.