The Cellular Prion Protein—ROCK Connection: Contribution to Neuronal Homeostasis and Neurodegenerative Diseases

The Cellular Prion Protein—ROCK Connection: Contribution to Neuronal Homeostasis and Neurodegenerative Diseases

Amyloid-based neurodegenerative diseases such as prion, Alzheimer's, and Parkinson's diseases have distinct etiologies and clinical manifestations, but they share common pathological events. These diseases are caused by abnormally folded proteins (pathogenic prions PrPSc in prion diseases,...

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Bibliographic Details
Main Authors: Benoit Schneider, Anne Baudry, Mathéa Pietri, Aurélie Alleaume-Butaux, Chloé Bizingre, Pierre Nioche, Odile Kellermann, Jean-Marie Launay
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Cellular Neuroscience
Subjects:
prion
signaling
neuronal differentiation
cytoskeleton
inflammation
unfolded protein response
Online Access:https://www.frontiersin.org/articles/10.3389/fncel.2021.660683/full

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