A Review of the 2019 Novel Coronavirus (Covid-19): Immunopathogenesis, Molecular Biology and Clinical Aspects

• Main Authors: Ali Ganji, Ghasem Mosayebi, Mohsen Khaki, Ali Ghazavi
• Format: Article
• Language: fas
• Published: Arak Medical University 2020-04-01
• Series: Majallah-i dānishgāh-i ̒ulūm-i pizishkī-i Arāk
• Subjects: coronavirus; covid-19; respiratory infection
• Online Access: http://jams.arakmu.ac.ir/article-1-6296-en.html

Background and Aim: COVID-19, a viral respiratory illness. In this review, we discuss issues such as the genetic structure, pathogenic mechanism, clinical characteristics, diagnosis, treatment, and prevention of COVID-19 based on the latest findings. Materials and Methods: The Medline was searched for terms such as “Coronavirus” ،“ COVID-19” and “Respiratory infection”. Findings: In December 2019, the unprecedented outbreak of pneumonia with unknown etiology began in Wuhan, Hubei Province, China. The cause was a new coronavirus, named COVID-19 by the WHO. This virus has high transmissibility and affects the lower respiratory tract. Research into the mechanism and treatment of COVID-19 is under way, and new information is being provided every day, some of which are contradictory. COVID-19 is a serious and dangerous infectious disease and a significant threat to the health of the world's population, and should be prevented from spreading rapidly. Conclusion: Because the exact mechanisms of the disease have not been fully elucidated and specific drug or vaccine have not yet been developed for it, control is mainly based on the interruption of the transmission cycle.