Inhibition of BMP signaling in P-Cadherin positive hair progenitor cells leads to trichofolliculoma-like hair follicle neoplasias

Inhibition of BMP signaling in P-Cadherin positive hair progenitor cells leads to trichofolliculoma-like hair follicle neoplasias

<p>Abstract</p> <p>Background</p> <p>Skin stem cells contribute to all three major lineages of epidermal appendages, i.e., the epidermis, the hair follicle, and the sebaceous gland. In hair follicles, highly proliferative committed progenitor cells, called matrix cells,...

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Bibliographic Details
Main Authors: Kan Lixin, Liu Yijie, McGuire Tammy L, Bonaguidi Michael A, Kessler John A
Format: Article
Language:English
Published: BMC 2011-12-01
Series:Journal of Biomedical Science
Subjects:
Transgenic Mice
Nse-Noggin
bone morphogenetic protein (BMP)
trichofolliculoma
Online Access:http://www.jbiomedsci.com/content/18/1/92

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