Study on Changes of the Urea, Serum Creatinine and Glomerular Protein Permeability, after General Anesthesia with Sevoflurane

Introduction: The widespread use of sevoflurane as an induction and maintenance volatile agent of general anesthesia demostrates an increased safety profile. Sevoflurane contact with CO2 absorbents lead to the occurrence of toxic compounds such as Compund A and Compound B. Among the side efffects of...

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Main Authors:	Mircea Stoian, Adina Stoian, Dumitru Costel, Florin Tripon, Iudita Badea, Leonard Azamfirei
Format:	Article
Language:	English
Published:	Sciendo 2015-09-01
Series:	Acta Medica Marisiensis
Subjects:	sevoflurane proteinuria creatinine blood urea nitrogen
Online Access:	https://doi.org/10.1515/amma-2015-0053

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spelling	doaj-b13d66c45c25435199059f836f1b36912021-09-06T19:39:51ZengSciendoActa Medica Marisiensis2247-61132015-09-0161317617910.1515/amma-2015-0053amma-2015-0053Study on Changes of the Urea, Serum Creatinine and Glomerular Protein Permeability, after General Anesthesia with SevofluraneMircea Stoian0Adina Stoian1Dumitru Costel2Florin Tripon3Iudita Badea4Leonard Azamfirei5University of Medicine and Pharmacy of Tirgu Mureș, RomâniaUniversity of Medicine and Pharmacy of Tirgu Mureș, RomâniaUniversity of Medicine and Pharmacy of Tirgu Mureș, RomâniaUniversity of Medicine and Pharmacy of Tirgu Mureș, RomâniaUniversity of Medicine and Pharmacy of Tirgu Mureș, RomâniaUniversity of Medicine and Pharmacy of Tirgu Mureș, RomâniaIntroduction: The widespread use of sevoflurane as an induction and maintenance volatile agent of general anesthesia demostrates an increased safety profile. Sevoflurane contact with CO2 absorbents lead to the occurrence of toxic compounds such as Compund A and Compound B. Among the side efffects of Sevoflurane remember the renal toxic effect much discussed in the literature but still unresolved. In previous research we have demonstrated the glomerular protein changes as a result of exposure to Sevoflurane. In the current study we intend to monitor the changes in blood urea nitrogen and serum creatinine after exposure to Sevoflurane.https://doi.org/10.1515/amma-2015-0053sevofluraneproteinuriacreatinineblood urea nitrogen
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Mircea Stoian Adina Stoian Dumitru Costel Florin Tripon Iudita Badea Leonard Azamfirei
spellingShingle	Mircea Stoian Adina Stoian Dumitru Costel Florin Tripon Iudita Badea Leonard Azamfirei Study on Changes of the Urea, Serum Creatinine and Glomerular Protein Permeability, after General Anesthesia with Sevoflurane Acta Medica Marisiensis sevoflurane proteinuria creatinine blood urea nitrogen
author_facet	Mircea Stoian Adina Stoian Dumitru Costel Florin Tripon Iudita Badea Leonard Azamfirei
author_sort	Mircea Stoian
title	Study on Changes of the Urea, Serum Creatinine and Glomerular Protein Permeability, after General Anesthesia with Sevoflurane
title_short	Study on Changes of the Urea, Serum Creatinine and Glomerular Protein Permeability, after General Anesthesia with Sevoflurane
title_full	Study on Changes of the Urea, Serum Creatinine and Glomerular Protein Permeability, after General Anesthesia with Sevoflurane
title_fullStr	Study on Changes of the Urea, Serum Creatinine and Glomerular Protein Permeability, after General Anesthesia with Sevoflurane
title_full_unstemmed	Study on Changes of the Urea, Serum Creatinine and Glomerular Protein Permeability, after General Anesthesia with Sevoflurane
title_sort	study on changes of the urea, serum creatinine and glomerular protein permeability, after general anesthesia with sevoflurane
publisher	Sciendo
series	Acta Medica Marisiensis
issn	2247-6113
publishDate	2015-09-01
description	Introduction: The widespread use of sevoflurane as an induction and maintenance volatile agent of general anesthesia demostrates an increased safety profile. Sevoflurane contact with CO2 absorbents lead to the occurrence of toxic compounds such as Compund A and Compound B. Among the side efffects of Sevoflurane remember the renal toxic effect much discussed in the literature but still unresolved. In previous research we have demonstrated the glomerular protein changes as a result of exposure to Sevoflurane. In the current study we intend to monitor the changes in blood urea nitrogen and serum creatinine after exposure to Sevoflurane.
topic	sevoflurane proteinuria creatinine blood urea nitrogen
url	https://doi.org/10.1515/amma-2015-0053
work_keys_str_mv	AT mirceastoian studyonchangesoftheureaserumcreatinineandglomerularproteinpermeabilityaftergeneralanesthesiawithsevoflurane AT adinastoian studyonchangesoftheureaserumcreatinineandglomerularproteinpermeabilityaftergeneralanesthesiawithsevoflurane AT dumitrucostel studyonchangesoftheureaserumcreatinineandglomerularproteinpermeabilityaftergeneralanesthesiawithsevoflurane AT florintripon studyonchangesoftheureaserumcreatinineandglomerularproteinpermeabilityaftergeneralanesthesiawithsevoflurane AT iuditabadea studyonchangesoftheureaserumcreatinineandglomerularproteinpermeabilityaftergeneralanesthesiawithsevoflurane AT leonardazamfirei studyonchangesoftheureaserumcreatinineandglomerularproteinpermeabilityaftergeneralanesthesiawithsevoflurane
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Study on Changes of the Urea, Serum Creatinine and Glomerular Protein Permeability, after General Anesthesia with Sevoflurane

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