Steady state analysis of influx and transbilayer distribution of ergosterol in the yeast plasma membrane
Abstract Background The transbilayer sterol distribution between both plasma membrane (PM) leaflets has long been debated. Recent studies in mammalian cells and in yeast show that the majority of sterol resides in the inner PM leaflet. Since sterol flip-flop in model membranes is rapid and energy-in...
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| Format: | Article |
| Language: | English |
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BMC
2019-08-01
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| Series: | Theoretical Biology and Medical Modelling |
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| Online Access: | http://link.springer.com/article/10.1186/s12976-019-0108-2 |