OSTEONECTIN AND SELECTED BIOMARKERS IN ATHEROSCLEROTIC OCCLUSION AND CALCINOSIS OF CORONARY ARTERIES

OSTEONECTIN AND SELECTED BIOMARKERS IN ATHEROSCLEROTIC OCCLUSION AND CALCINOSIS OF CORONARY ARTERIES

Blood levels of osteonectin (a protein marker of stromal stem cells with osteogenic potential) were measured, using the method of biomagnetic protein separation with magnetic microspheres, in 45 men with coronary atherosclerosis and 45 age-matched controls without coronary heart disease. Osteonectin...

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Bibliographic Details
Main Authors: Yu. I. Ragino, E. V. Kashtanova, A. M. Chernyavsky, A. M. Volkov, Ya. V. Polonskaya, M. V. Ivanova
Format: Article
Language:Russian
Published: «FIRMA «SILICEA» LLC  2010-08-01
Series:Российский кардиологический журнал
Subjects:
osteonectin
atherosclerotic stenosis and calcinosis of coronary arteries
atherosclerosis biomarkers
Online Access:https://russjcardiol.elpub.ru/jour/article/view/1463
Description
Summary:Blood levels of osteonectin (a protein marker of stromal stem cells with osteogenic potential) were measured, using the method of biomagnetic protein separation with magnetic microspheres, in 45 men with coronary atherosclerosis and 45 age-matched controls without coronary heart disease. Osteonectin concentration was maximal in men with atherosclerotic stenosis (AS) and calcinosis of coronary arteries. Osteonectin levels were independently associated with several key markers of atherosclerosis, metabolic syndrome, and coronary AS and calcinosis. Therefore, osteonectin could be one of the new markers of coronary AS and calcinosis.
ISSN:1560-4071
2618-7620

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