Magnetic Nanoparticles: From Design and Synthesis to Real World Applications
The increasing number of scientific publications focusing on magnetic materials indicates growing interest in the broader scientific community. Substantial progress was made in the synthesis of magnetic materials of desired size, morphology, chemical composition, and surface chemistry. Physical and...
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doaj-b156e6e6ac134ac1a7e74277e4dc27382020-11-25T02:29:16ZengMDPI AGNanomaterials2079-49912017-08-017924310.3390/nano7090243nano7090243Magnetic Nanoparticles: From Design and Synthesis to Real World ApplicationsJiri Kudr0Yazan Haddad1Lukas Richtera2Zbynek Heger3Mirko Cernak4Vojtech Adam5Ondrej Zitka6Department of Chemistry and Biochemistry, Mendel University in Brno, Zemedelska 1, CZ-61300 Brno, Czech RepublicDepartment of Chemistry and Biochemistry, Mendel University in Brno, Zemedelska 1, CZ-61300 Brno, Czech RepublicDepartment of Chemistry and Biochemistry, Mendel University in Brno, Zemedelska 1, CZ-61300 Brno, Czech RepublicDepartment of Chemistry and Biochemistry, Mendel University in Brno, Zemedelska 1, CZ-61300 Brno, Czech RepublicCEPLANT R&D Centre for Low-Cost Plasma and Nanotechnology Surface Modifications, Masaryk University, Kotlarska 2, CZ-61137 Brno, Czech RepublicDepartment of Chemistry and Biochemistry, Mendel University in Brno, Zemedelska 1, CZ-61300 Brno, Czech RepublicDepartment of Chemistry and Biochemistry, Mendel University in Brno, Zemedelska 1, CZ-61300 Brno, Czech RepublicThe increasing number of scientific publications focusing on magnetic materials indicates growing interest in the broader scientific community. Substantial progress was made in the synthesis of magnetic materials of desired size, morphology, chemical composition, and surface chemistry. Physical and chemical stability of magnetic materials is acquired by the coating. Moreover, surface layers of polymers, silica, biomolecules, etc. can be designed to obtain affinity to target molecules. The combination of the ability to respond to the external magnetic field and the rich possibilities of coatings makes magnetic materials universal tool for magnetic separations of small molecules, biomolecules and cells. In the biomedical field, magnetic particles and magnetic composites are utilized as the drug carriers, as contrast agents for magnetic resonance imaging (MRI), and in magnetic hyperthermia. However, the multifunctional magnetic particles enabling the diagnosis and therapy at the same time are emerging. The presented review article summarizes the findings regarding the design and synthesis of magnetic materials focused on biomedical applications. We highlight the utilization of magnetic materials in separation/preconcentration of various molecules and cells, and their use in diagnosis and therapy.https://www.mdpi.com/2079-4991/7/9/243magnetic resonance imagingnanocarriernanoscalepreconcentrationseparationsilicatheranosticstherapeutic agents |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Jiri Kudr Yazan Haddad Lukas Richtera Zbynek Heger Mirko Cernak Vojtech Adam Ondrej Zitka |
spellingShingle |
Jiri Kudr Yazan Haddad Lukas Richtera Zbynek Heger Mirko Cernak Vojtech Adam Ondrej Zitka Magnetic Nanoparticles: From Design and Synthesis to Real World Applications Nanomaterials magnetic resonance imaging nanocarrier nanoscale preconcentration separation silica theranostics therapeutic agents |
author_facet |
Jiri Kudr Yazan Haddad Lukas Richtera Zbynek Heger Mirko Cernak Vojtech Adam Ondrej Zitka |
author_sort |
Jiri Kudr |
title |
Magnetic Nanoparticles: From Design and Synthesis to Real World Applications |
title_short |
Magnetic Nanoparticles: From Design and Synthesis to Real World Applications |
title_full |
Magnetic Nanoparticles: From Design and Synthesis to Real World Applications |
title_fullStr |
Magnetic Nanoparticles: From Design and Synthesis to Real World Applications |
title_full_unstemmed |
Magnetic Nanoparticles: From Design and Synthesis to Real World Applications |
title_sort |
magnetic nanoparticles: from design and synthesis to real world applications |
publisher |
MDPI AG |
series |
Nanomaterials |
issn |
2079-4991 |
publishDate |
2017-08-01 |
description |
The increasing number of scientific publications focusing on magnetic materials indicates growing interest in the broader scientific community. Substantial progress was made in the synthesis of magnetic materials of desired size, morphology, chemical composition, and surface chemistry. Physical and chemical stability of magnetic materials is acquired by the coating. Moreover, surface layers of polymers, silica, biomolecules, etc. can be designed to obtain affinity to target molecules. The combination of the ability to respond to the external magnetic field and the rich possibilities of coatings makes magnetic materials universal tool for magnetic separations of small molecules, biomolecules and cells. In the biomedical field, magnetic particles and magnetic composites are utilized as the drug carriers, as contrast agents for magnetic resonance imaging (MRI), and in magnetic hyperthermia. However, the multifunctional magnetic particles enabling the diagnosis and therapy at the same time are emerging. The presented review article summarizes the findings regarding the design and synthesis of magnetic materials focused on biomedical applications. We highlight the utilization of magnetic materials in separation/preconcentration of various molecules and cells, and their use in diagnosis and therapy. |
topic |
magnetic resonance imaging nanocarrier nanoscale preconcentration separation silica theranostics therapeutic agents |
url |
https://www.mdpi.com/2079-4991/7/9/243 |
work_keys_str_mv |
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