Determining crystal structures through crowdsourcing and coursework
Building crystal structures into the electron density is an important step in protein structure solution. Here, the authors recruit online game players, students, and experienced crystallographers to compete in a competition to solve a new structure, and find that crowdsourcing model-building works.
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Nature Publishing Group
2016-09-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/ncomms12549 |
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doaj-b15fb233272548d7bc0404a5bf35e26f2021-05-11T10:34:59ZengNature Publishing GroupNature Communications2041-17232016-09-017111110.1038/ncomms12549Determining crystal structures through crowdsourcing and courseworkScott Horowitz0Brian Koepnick1Raoul Martin2Agnes Tymieniecki3Amanda A. Winburn4Seth Cooper5Jeff Flatten6David S. Rogawski7Nicole M. Koropatkin8Tsinatkeab T. Hailu9Neha Jain10Philipp Koldewey11Logan S. Ahlstrom12Matthew R. Chapman13Andrew P. Sikkema14Meredith A. Skiba15Finn P. Maloney16Felix R. M. Beinlich17Foldit PlayersUniversity of Michigan studentsZoran Popović18David Baker19Firas Khatib20James C. A. Bardwell21Department of Molecular, Cellular, and Developmental Biology, University of MichiganDepartment of Biochemistry, University of WashingtonDepartment of Molecular, Cellular, and Developmental Biology, University of MichiganDepartment of Molecular, Cellular, and Developmental Biology, University of MichiganDepartment of Informatics, Center for Complex Networks and Systems Research, Indiana UniversityNortheastern University, College of Computer and Information ScienceDepartment of Computer Science and Engineering, Center for Game Science, University of WashingtonDepartment of Pathology, University of MichiganDepartment of Microbiology and Immunology, University of MichiganDepartment of Molecular, Cellular, and Developmental Biology, University of MichiganDepartment of Molecular, Cellular, and Developmental Biology, University of MichiganDepartment of Molecular, Cellular, and Developmental Biology, University of MichiganDepartment of Molecular, Cellular, and Developmental Biology, University of MichiganDepartment of Molecular, Cellular, and Developmental Biology, University of MichiganDepartment of Biological Chemistry and Life Sciences Institute, University of MichiganDepartment of Biological Chemistry and Life Sciences Institute, University of MichiganChemical Biology Doctoral Program, University of MichiganDepartment of Molecular, Cellular, and Developmental Biology, University of MichiganDepartment of Computer Science and Engineering, Center for Game Science, University of WashingtonDepartment of Biochemistry, University of WashingtonDepartment of Computer and Information Science, University of Massachusetts DartmouthDepartment of Molecular, Cellular, and Developmental Biology, University of MichiganBuilding crystal structures into the electron density is an important step in protein structure solution. Here, the authors recruit online game players, students, and experienced crystallographers to compete in a competition to solve a new structure, and find that crowdsourcing model-building works.https://doi.org/10.1038/ncomms12549 |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
Scott Horowitz Brian Koepnick Raoul Martin Agnes Tymieniecki Amanda A. Winburn Seth Cooper Jeff Flatten David S. Rogawski Nicole M. Koropatkin Tsinatkeab T. Hailu Neha Jain Philipp Koldewey Logan S. Ahlstrom Matthew R. Chapman Andrew P. Sikkema Meredith A. Skiba Finn P. Maloney Felix R. M. Beinlich Foldit Players University of Michigan students Zoran Popović David Baker Firas Khatib James C. A. Bardwell |
| spellingShingle |
Scott Horowitz Brian Koepnick Raoul Martin Agnes Tymieniecki Amanda A. Winburn Seth Cooper Jeff Flatten David S. Rogawski Nicole M. Koropatkin Tsinatkeab T. Hailu Neha Jain Philipp Koldewey Logan S. Ahlstrom Matthew R. Chapman Andrew P. Sikkema Meredith A. Skiba Finn P. Maloney Felix R. M. Beinlich Foldit Players University of Michigan students Zoran Popović David Baker Firas Khatib James C. A. Bardwell Determining crystal structures through crowdsourcing and coursework Nature Communications |
| author_facet |
Scott Horowitz Brian Koepnick Raoul Martin Agnes Tymieniecki Amanda A. Winburn Seth Cooper Jeff Flatten David S. Rogawski Nicole M. Koropatkin Tsinatkeab T. Hailu Neha Jain Philipp Koldewey Logan S. Ahlstrom Matthew R. Chapman Andrew P. Sikkema Meredith A. Skiba Finn P. Maloney Felix R. M. Beinlich Foldit Players University of Michigan students Zoran Popović David Baker Firas Khatib James C. A. Bardwell |
| author_sort |
Scott Horowitz |
| title |
Determining crystal structures through crowdsourcing and coursework |
| title_short |
Determining crystal structures through crowdsourcing and coursework |
| title_full |
Determining crystal structures through crowdsourcing and coursework |
| title_fullStr |
Determining crystal structures through crowdsourcing and coursework |
| title_full_unstemmed |
Determining crystal structures through crowdsourcing and coursework |
| title_sort |
determining crystal structures through crowdsourcing and coursework |
| publisher |
Nature Publishing Group |
| series |
Nature Communications |
| issn |
2041-1723 |
| publishDate |
2016-09-01 |
| description |
Building crystal structures into the electron density is an important step in protein structure solution. Here, the authors recruit online game players, students, and experienced crystallographers to compete in a competition to solve a new structure, and find that crowdsourcing model-building works. |
| url |
https://doi.org/10.1038/ncomms12549 |
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