The PYY/Y2R-Deficient Mouse Responds Normally to High-Fat Diet and Gastric Bypass Surgery

The PYY/Y2R-Deficient Mouse Responds Normally to High-Fat Diet and Gastric Bypass Surgery

Background/Goals: The gut hormone peptide YY (PYY) secreted from intestinal L-cells has been implicated in the mechanisms of satiation via Y2-receptor (Y2R) signaling in the brain and periphery and is a major candidate for mediating the beneficial effects of bariatric surgery on appetite and body we...

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Bibliographic Details
Main Authors: Brandon Boland, Michael B. Mumphrey, Zheng Hao, Benji Gill, R. Leigh Townsend, Sangho Yu, Heike Münzberg, Christopher D. Morrison, James L. Trevaskis, Hans-Rudolf Berthoud
Format: Article
Language:English
Published: MDPI AG 2019-03-01
Series:Nutrients
Subjects:
obesity
diabetes
body weight
body composition
glucose tolerance
insulin tolerance
incretin
energy expenditure
Online Access:http://www.mdpi.com/2072-6643/11/3/585

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