Warning of Immortal Time Bias When Studying Drug Safety in Pregnancy: Application to Late Use of Antibiotics and Preterm Delivery

This study aimed to illustrate and account for immortal time bias in pregnancy observational investigations, using the relationship between late use of antibiotics and risk of preterm birth as an example. We conducted a population-based cohort study including 549,082 deliveries between 2007 and 2017...

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Bibliographic Details
Main Authors: Giovanni Corrao, Federico Rea, Matteo Franchi, Benedetta Beccalli, Anna Locatelli, Anna Cantarutti
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:International Journal of Environmental Research and Public Health
Subjects:
Online Access:https://www.mdpi.com/1660-4601/17/18/6465