Upregulation of pulmonary tissue factor, loss of thrombomodulin and immunothrombosis in SARS-CoV-2 infection
Background: SARS-CoV-2 infection is associated with thrombotic and microvascular complications. The cause of coagulopathy in the disease is incompletely understood. Methods: A single-center cross-sectional study including 66 adult COVID-19 patients (40 moderate, 26 severe disease), and 9 controls, p...
Main Authors: | Ivo M.B. Francischetti, Kevin Toomer, Yifan Zhang, Jayesh Jani, Zishan Siddiqui, Daniel J. Brotman, Jody E. Hooper, Thomas S. Kickler |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2021-09-01
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Series: | EClinicalMedicine |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2589537021003497 |
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