A-to-I RNA editing: current knowledge sources and computational approaches with special emphasis on non-coding RNA molecules

RNA editing is a dynamic mechanism for gene regulation attained through the alteration of the sequence of primary RNA transcripts. A-to-I (Adenosine-to-Inosine) RNA editing, which is catalyzed by members of the Adenosine Deaminase Acting on RNA (ADAR) family of enzymes, is the most common post-trans...

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Bibliographic Details
Main Authors: Giovanni eNigita, Dario eVeneziano, Alfredo eFerro
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-03-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
HTS
Online Access:http://journal.frontiersin.org/Journal/10.3389/fbioe.2015.00037/full