Thiocyanation of Pyrazoles Using KSCN/K2S2O8 Combination

Thiocyanation of Pyrazoles Using KSCN/K2S2O8 Combination

Abstract A convenient and practical thiocyanation of pyrazoles is reported employing a combination of KSCN and K2S2O8 in dimethyl sulfoxide (DMSO). The salient features of the present reaction include environmentally benign reagents and solvents, and simple operation. The reaction shows wide functio...

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Bibliographic Details
Main Authors: T. Songsichan, P. Katrun, O. Khaikate, D. Soorukram, M. Pohmakotr, V. Reutrakul, C. Kuhakarn
Format: Article
Language:English
Published: Georg Thieme Verlag KG 2018-01-01
Series:SynOpen
Subjects:
thiocyanation
pyrazoles
potassium thiocyanate
potassium persulfate
heterocycle
Online Access:http://www.thieme-connect.de/DOI/DOI?10.1055/s-0036-1591891
Description
Summary:Abstract A convenient and practical thiocyanation of pyrazoles is reported employing a combination of KSCN and K2S2O8 in dimethyl sulfoxide (DMSO). The salient features of the present reaction include environmentally benign reagents and solvents, and simple operation. The reaction shows wide functional group tolerance and gives moderate to excellent yields.
ISSN:2509-9396

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