Ethyl 2-[2-(4-Nitrobenzoyl)-1H-indol-3-yl]acetate
Ethyl 2-[2-(4-nitrobenzoyl)-1H-indol-3-yl]acetate was prepared in good yield and characterized by the aza-alkylation/intramolecular Michael cascade reaction of (E)-ethyl 3-[2-(tosylamino)phenyl]acrylate with 2-bromo-4′′-nitroacetophenone, followed by desulfonative dehydrogenation with 1,8-diazabicyc...
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MDPI AG
2017-07-01
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| Series: | Molbank |
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| Online Access: | https://www.mdpi.com/1422-8599/2017/3/M945 |
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doaj-b1c8cb1a5b5d4d5bb331455bb0a6c4f82020-11-25T00:56:22ZengMDPI AGMolbank1422-85992017-07-0120173M94510.3390/M945M945Ethyl 2-[2-(4-Nitrobenzoyl)-1H-indol-3-yl]acetateSunyoung Choi0Sung-Gon Kim1Department of Chemistry, Kyonggi University,154-42, Gwanggyosan-ro, Yeongtong-gu, Suwon 16227, KoreaDepartment of Chemistry, Kyonggi University,154-42, Gwanggyosan-ro, Yeongtong-gu, Suwon 16227, KoreaEthyl 2-[2-(4-nitrobenzoyl)-1H-indol-3-yl]acetate was prepared in good yield and characterized by the aza-alkylation/intramolecular Michael cascade reaction of (E)-ethyl 3-[2-(tosylamino)phenyl]acrylate with 2-bromo-4′′-nitroacetophenone, followed by desulfonative dehydrogenation with 1,8-diazabicyclo[5.4.0]undec-7-ene (DBU) The structure of the newly synthesized compound was determined using 1H-,13C-NMR, IR and mass spectral data.https://www.mdpi.com/1422-8599/2017/3/M945IndoleMichael reactiondehydrogenationcascade reaction |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
Sunyoung Choi Sung-Gon Kim |
| spellingShingle |
Sunyoung Choi Sung-Gon Kim Ethyl 2-[2-(4-Nitrobenzoyl)-1H-indol-3-yl]acetate Molbank Indole Michael reaction dehydrogenation cascade reaction |
| author_facet |
Sunyoung Choi Sung-Gon Kim |
| author_sort |
Sunyoung Choi |
| title |
Ethyl 2-[2-(4-Nitrobenzoyl)-1H-indol-3-yl]acetate |
| title_short |
Ethyl 2-[2-(4-Nitrobenzoyl)-1H-indol-3-yl]acetate |
| title_full |
Ethyl 2-[2-(4-Nitrobenzoyl)-1H-indol-3-yl]acetate |
| title_fullStr |
Ethyl 2-[2-(4-Nitrobenzoyl)-1H-indol-3-yl]acetate |
| title_full_unstemmed |
Ethyl 2-[2-(4-Nitrobenzoyl)-1H-indol-3-yl]acetate |
| title_sort |
ethyl 2-[2-(4-nitrobenzoyl)-1h-indol-3-yl]acetate |
| publisher |
MDPI AG |
| series |
Molbank |
| issn |
1422-8599 |
| publishDate |
2017-07-01 |
| description |
Ethyl 2-[2-(4-nitrobenzoyl)-1H-indol-3-yl]acetate was prepared in good yield and characterized by the aza-alkylation/intramolecular Michael cascade reaction of (E)-ethyl 3-[2-(tosylamino)phenyl]acrylate with 2-bromo-4′′-nitroacetophenone, followed by desulfonative dehydrogenation with 1,8-diazabicyclo[5.4.0]undec-7-ene (DBU) The structure of the newly synthesized compound was determined using 1H-,13C-NMR, IR and mass spectral data. |
| topic |
Indole Michael reaction dehydrogenation cascade reaction |
| url |
https://www.mdpi.com/1422-8599/2017/3/M945 |
| work_keys_str_mv |
AT sunyoungchoi ethyl224nitrobenzoyl1hindol3ylacetate AT sunggonkim ethyl224nitrobenzoyl1hindol3ylacetate |
| _version_ |
1725227573369110528 |