Detection of Cryptococcus Neoformans By Seminested Pcr in Cerebrospinal Fluid

Detection of Cryptococcus Neoformans By Seminested Pcr in Cerebrospinal Fluid

Life-threatening infections caused by the encapsulated fungal pathogen Cryptococcus neoformans have been increasing steadily over the past 10 years.Cryptococcus neoformans is recognized as the most frequent fungal infection of the central nervous system (CNS) in immunocompetent as well as immunocomp...

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Bibliographic Details
Main Authors: ALI ASGHAR KHAKSAR, MANSOOR ABACHI, SHAHINDOKHT BASSIRI JAHROMI
Format: Article
Language:English
Published: Iran University of Medical Sciences 2006-07-01
Series:Medical Journal of The Islamic Republic of Iran
Subjects:
Cryptococcus neoformans
PCR
Semi-nested PCR
CSF
Online Access:http://mjiri.tums.ac.ir/browse.php?a_code=A-10-1-209&slc_lang=en&sid=1
Description
Summary:Life-threatening infections caused by the encapsulated fungal pathogen Cryptococcus neoformans have been increasing steadily over the past 10 years.Cryptococcus neoformans is recognized as the most frequent fungal infection of the central nervous system (CNS) in immunocompetent as well as immunocompromised patients.We report the development of a semi-nested- PCR-based assay for the detection of C.neoformans in less than 100 yeast cells per ml of cerebrospinal fluid(CSF).
ISSN:1016-1430
2251-6840

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