Exposure to MIV-150 from a high-dose intravaginal ring results in limited emergence of drug resistance mutations in SHIV-RT infected rhesus macaques.
When microbicides used for HIV prevention contain antiretroviral drugs, there is concern for the potential emergence of drug-resistant HIV following use in infected individuals who are either unaware of their HIV infection status or who are aware but still choose to use the microbicide. Resistant vi...
Main Authors: | Mayla Hsu, Brandon F Keele, Meropi Aravantinou, Noa Krawczyk, Samantha Seidor, Ciby J Abraham, Shimin Zhang, Aixa Rodriguez, Larisa Kizima, Nina Derby, Ninochka Jean-Pierre, Olga Mizenina, Agegnehu Gettie, Brooke Grasperge, James Blanchard, Michael J Piatak, Jeffrey D Lifson, José A Fernández-Romero, Thomas M Zydowsky, Melissa Robbiani |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2014-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3937329?pdf=render |
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