A Young Adult Patient with Nonalcoholic Steatohepatitis Developed Severe Gastroesophageal Varices Associated with Severe Obesity and Diabetes Mellitus

• Main Authors: Yuichi Honma, Kazuhiro Sumida, Noriyoshi Ogino, Masashi Kusanaga, Sota Minami, Shinsuke Kumei, Hidehiko Matsuoka, Tatsuyuki Watanabe, Masaaki Hiura, Shintaro Abe, Michihiko Shibata, Masaru Harada
• Format: Article
• Language: English
• Published: Karger Publishers 2018-08-01
• Series: Case Reports in Gastroenterology
• Subjects: Nonalcoholic steatohepatitis; Young patient; Insulin resistance; Obesity; Gastroesophageal varices
• Online Access: https://www.karger.com/Article/FullText/492423
• ISSN: 1662-0631

Obesity is a major contributor to insulin resistance and nonalcoholic fatty liver disease, which is the most common cause of chronic liver diseases. Nonalcoholic steatohepatitis (NASH) can progress to liver cirrhosis and end-stage liver diseases. Some cases already show severe liver fibrosis at the time of diagnosis. We present the case of a 44-year-old male with overt obesity who was admitted with hematemesis due to the rupture of gastric varices. We diagnosed him with NASH with severe liver fibrosis. This case shows that we should be concerned about the progression of liver fibrosis due to NASH associated with severe obesity even in young patients.