A Young Adult Patient with Nonalcoholic Steatohepatitis Developed Severe Gastroesophageal Varices Associated with Severe Obesity and Diabetes Mellitus
Obesity is a major contributor to insulin resistance and nonalcoholic fatty liver disease, which is the most common cause of chronic liver diseases. Nonalcoholic steatohepatitis (NASH) can progress to liver cirrhosis and end-stage liver diseases. Some cases already show severe liver fibrosis at the...
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| Language: | English |
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Karger Publishers
2018-08-01
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| Series: | Case Reports in Gastroenterology |
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| Online Access: | https://www.karger.com/Article/FullText/492423 |
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doaj-b232b3d2eed94a1c9d5bc9784507d7512020-11-25T00:54:33ZengKarger PublishersCase Reports in Gastroenterology1662-06312018-08-0112248749610.1159/000492423492423A Young Adult Patient with Nonalcoholic Steatohepatitis Developed Severe Gastroesophageal Varices Associated with Severe Obesity and Diabetes MellitusYuichi HonmaKazuhiro SumidaNoriyoshi OginoMasashi KusanagaSota MinamiShinsuke KumeiHidehiko MatsuokaTatsuyuki WatanabeMasaaki HiuraShintaro AbeMichihiko ShibataMasaru HaradaObesity is a major contributor to insulin resistance and nonalcoholic fatty liver disease, which is the most common cause of chronic liver diseases. Nonalcoholic steatohepatitis (NASH) can progress to liver cirrhosis and end-stage liver diseases. Some cases already show severe liver fibrosis at the time of diagnosis. We present the case of a 44-year-old male with overt obesity who was admitted with hematemesis due to the rupture of gastric varices. We diagnosed him with NASH with severe liver fibrosis. This case shows that we should be concerned about the progression of liver fibrosis due to NASH associated with severe obesity even in young patients.https://www.karger.com/Article/FullText/492423Nonalcoholic steatohepatitisYoung patientInsulin resistanceObesityGastroesophageal varices |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
Yuichi Honma Kazuhiro Sumida Noriyoshi Ogino Masashi Kusanaga Sota Minami Shinsuke Kumei Hidehiko Matsuoka Tatsuyuki Watanabe Masaaki Hiura Shintaro Abe Michihiko Shibata Masaru Harada |
| spellingShingle |
Yuichi Honma Kazuhiro Sumida Noriyoshi Ogino Masashi Kusanaga Sota Minami Shinsuke Kumei Hidehiko Matsuoka Tatsuyuki Watanabe Masaaki Hiura Shintaro Abe Michihiko Shibata Masaru Harada A Young Adult Patient with Nonalcoholic Steatohepatitis Developed Severe Gastroesophageal Varices Associated with Severe Obesity and Diabetes Mellitus Case Reports in Gastroenterology Nonalcoholic steatohepatitis Young patient Insulin resistance Obesity Gastroesophageal varices |
| author_facet |
Yuichi Honma Kazuhiro Sumida Noriyoshi Ogino Masashi Kusanaga Sota Minami Shinsuke Kumei Hidehiko Matsuoka Tatsuyuki Watanabe Masaaki Hiura Shintaro Abe Michihiko Shibata Masaru Harada |
| author_sort |
Yuichi Honma |
| title |
A Young Adult Patient with Nonalcoholic Steatohepatitis Developed Severe Gastroesophageal Varices Associated with Severe Obesity and Diabetes Mellitus |
| title_short |
A Young Adult Patient with Nonalcoholic Steatohepatitis Developed Severe Gastroesophageal Varices Associated with Severe Obesity and Diabetes Mellitus |
| title_full |
A Young Adult Patient with Nonalcoholic Steatohepatitis Developed Severe Gastroesophageal Varices Associated with Severe Obesity and Diabetes Mellitus |
| title_fullStr |
A Young Adult Patient with Nonalcoholic Steatohepatitis Developed Severe Gastroesophageal Varices Associated with Severe Obesity and Diabetes Mellitus |
| title_full_unstemmed |
A Young Adult Patient with Nonalcoholic Steatohepatitis Developed Severe Gastroesophageal Varices Associated with Severe Obesity and Diabetes Mellitus |
| title_sort |
young adult patient with nonalcoholic steatohepatitis developed severe gastroesophageal varices associated with severe obesity and diabetes mellitus |
| publisher |
Karger Publishers |
| series |
Case Reports in Gastroenterology |
| issn |
1662-0631 |
| publishDate |
2018-08-01 |
| description |
Obesity is a major contributor to insulin resistance and nonalcoholic fatty liver disease, which is the most common cause of chronic liver diseases. Nonalcoholic steatohepatitis (NASH) can progress to liver cirrhosis and end-stage liver diseases. Some cases already show severe liver fibrosis at the time of diagnosis. We present the case of a 44-year-old male with overt obesity who was admitted with hematemesis due to the rupture of gastric varices. We diagnosed him with NASH with severe liver fibrosis. This case shows that we should be concerned about the progression of liver fibrosis due to NASH associated with severe obesity even in young patients. |
| topic |
Nonalcoholic steatohepatitis Young patient Insulin resistance Obesity Gastroesophageal varices |
| url |
https://www.karger.com/Article/FullText/492423 |
| work_keys_str_mv |
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