High rate of antimicrobial resistance and multiple mutations in the dihydrofolate reductase gene among Streptococcus pneumoniae isolated from HIV-infected adults in a community setting in Tanzania

High rate of antimicrobial resistance and multiple mutations in the dihydrofolate reductase gene among Streptococcus pneumoniae isolated from HIV-infected adults in a community setting in Tanzania

Objectives: The aim of this study was to characterize molecular mechanisms of resistance to trimethoprim and other antibiotics in Streptococcus pneumoniae isolates from HIV-infected adults in Dar es Salaam, Tanzania. Methods: A total of 1877 nasopharyngeal swabs were collected and screened for pneum...

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Bibliographic Details
Main Authors: Joel Manyahi, Sabrina Moyo, Said Aboud, Nina Langeland, Bjørn Blomberg
Format: Article
Language:English
Published: Elsevier 2020-09-01
Series:Journal of Global Antimicrobial Resistance
Subjects:
Antimicrobial resistance
Streptococcus pneumoniae
HIV
Tanzania
Dihydrofolate reductase
Online Access:http://www.sciencedirect.com/science/article/pii/S2213716520301715

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