Associations of the major international high-risk resistant clones and virulent clones with specific ompK36 allele groups in Klebsiella pneumoniae in Taiwan
This study was conducted to investigate the association between ompK36 variants and international high-risk clones in Klebsiella pneumoniae. Fifty-nine sequence types (STs) divided into four ompK36 allele groups (groups A to D) were identified among 185 K. pneumoniae isolates. The major high-risk cl...
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doaj-b24ee139d19b4a2a9143f66402b489092020-11-25T01:14:51ZengElsevierNew Microbes and New Infections2052-29752015-05-015C1410.1016/j.nmni.2015.01.002Associations of the major international high-risk resistant clones and virulent clones with specific ompK36 allele groups in Klebsiella pneumoniae in TaiwanJ.J. Yan0M.C. Wang1P.X. Zheng2L.H. Tsai3J.J. Wu4Department of Pathology, National Cheng Kung University College of Medicine and Hospital, TaiwanDepartment of Internal Medicine, National Cheng Kung University College of Medicine and Hospital, TaiwanInstitute of Basic Medical Sciences, College of Medicine, National Cheng Kung University, TaiwanDepartment of Pathology, National Cheng Kung University College of Medicine and Hospital, TaiwanDepartment of Medical Laboratory Science and Biotechnology, College of Medicine, National Cheng Kung University, TaiwanThis study was conducted to investigate the association between ompK36 variants and international high-risk clones in Klebsiella pneumoniae. Fifty-nine sequence types (STs) divided into four ompK36 allele groups (groups A to D) were identified among 185 K. pneumoniae isolates. The major high-risk clones (29 ST11, 13 ST15, 7 ST37 and 1 ST147 isolates) were assigned to group A, while 6 STs (15 ST23, 2 ST65, 3 ST86, 1 ST163, 1 ST373 and 2 ST375 isolates) associated with pyogenic liver abscess were assigned to group C. The genotyping assay developed in this study may be useful for screening of epidemic STs.http://www.sciencedirect.com/science/article/pii/S2052297515000219High-risk clonesKlebsiella pneumoniaemultilocus sequence typingpyogenic liver abscesssequence types |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
J.J. Yan M.C. Wang P.X. Zheng L.H. Tsai J.J. Wu |
spellingShingle |
J.J. Yan M.C. Wang P.X. Zheng L.H. Tsai J.J. Wu Associations of the major international high-risk resistant clones and virulent clones with specific ompK36 allele groups in Klebsiella pneumoniae in Taiwan New Microbes and New Infections High-risk clones Klebsiella pneumoniae multilocus sequence typing pyogenic liver abscess sequence types |
author_facet |
J.J. Yan M.C. Wang P.X. Zheng L.H. Tsai J.J. Wu |
author_sort |
J.J. Yan |
title |
Associations of the major international high-risk resistant clones and virulent clones with specific ompK36 allele groups in Klebsiella pneumoniae in Taiwan |
title_short |
Associations of the major international high-risk resistant clones and virulent clones with specific ompK36 allele groups in Klebsiella pneumoniae in Taiwan |
title_full |
Associations of the major international high-risk resistant clones and virulent clones with specific ompK36 allele groups in Klebsiella pneumoniae in Taiwan |
title_fullStr |
Associations of the major international high-risk resistant clones and virulent clones with specific ompK36 allele groups in Klebsiella pneumoniae in Taiwan |
title_full_unstemmed |
Associations of the major international high-risk resistant clones and virulent clones with specific ompK36 allele groups in Klebsiella pneumoniae in Taiwan |
title_sort |
associations of the major international high-risk resistant clones and virulent clones with specific ompk36 allele groups in klebsiella pneumoniae in taiwan |
publisher |
Elsevier |
series |
New Microbes and New Infections |
issn |
2052-2975 |
publishDate |
2015-05-01 |
description |
This study was conducted to investigate the association between ompK36 variants and international high-risk clones in Klebsiella pneumoniae. Fifty-nine sequence types (STs) divided into four ompK36 allele groups (groups A to D) were identified among 185 K. pneumoniae isolates. The major high-risk clones (29 ST11, 13 ST15, 7 ST37 and 1 ST147 isolates) were assigned to group A, while 6 STs (15 ST23, 2 ST65, 3 ST86, 1 ST163, 1 ST373 and 2 ST375 isolates) associated with pyogenic liver abscess were assigned to group C. The genotyping assay developed in this study may be useful for screening of epidemic STs. |
topic |
High-risk clones Klebsiella pneumoniae multilocus sequence typing pyogenic liver abscess sequence types |
url |
http://www.sciencedirect.com/science/article/pii/S2052297515000219 |
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