Gene Set−Based Integrative Analysis Revealing Two Distinct Functional Regulation Patterns in Four Common Subtypes of Epithelial Ovarian Cancer

Gene Set−Based Integrative Analysis Revealing Two Distinct Functional Regulation Patterns in Four Common Subtypes of Epithelial Ovarian Cancer

Clear cell (CCC), endometrioid (EC), mucinous (MC) and high-grade serous carcinoma (SC) are the four most common subtypes of epithelial ovarian carcinoma (EOC). The widely accepted dualistic model of ovarian carcinogenesis divided EOCs into type I and II categories based on the molecular features. H...

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Bibliographic Details
Main Authors: Chia-Ming Chang, Chi-Mu Chuang, Mong-Lien Wang, Yi-Ping Yang, Jen-Hua Chuang, Ming-Jie Yang, Ming-Shyen Yen, Shih-Hwa Chiou, Cheng-Chang Chang
Format: Article
Language:English
Published: MDPI AG 2016-08-01
Series:International Journal of Molecular Sciences
Subjects:
epithelial ovarian cancer
function
integrative analysis
gene expression microarray
gene set
machine learning
Online Access:http://www.mdpi.com/1422-0067/17/8/1272

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