Hydrogen-bonding patterns in the cocrystal 2-amino-4,6-dimethoxypyrimidine–anthranilic acid (1/1)

• Main Authors: Kaliyaperumal Thanigaimani, Packianathan Thomas Muthiah, Daniel E. Lynch
• Format: Article
• Language: English
• Published: International Union of Crystallography 2008-01-01
• Series: Acta Crystallographica Section E
• Online Access: http://scripts.iucr.org/cgi-bin/paper?S1600536807063271

In the title cocrystal, C6H9N3O2·C7H7NO2, the asymmetric unit contains two crystallographically independent 2-amino-4,6-dimethoxy pyrimidine-anthranilic acid adducts. The 2-amino-4,6-dimethoxy pyrimidine molecules interact with the carboxylic group of the respective anthranilic acid molecules through N—H...O and O—H...N hydrogen bonds, forming a cyclic hydrogen-bonded motif R22(8). The pyrimidine molecules also form base pairs via a pair of N—H...N hydrogen bonds, forming another R22(8) motif. The typical intramolecular N—H...O hydrogen bond is observed in the anthranilic acid molecules. Furthermore, the crystal structure is stabilized by C—H...O hydrogen bonds.